| Full name: tripartite motif containing 49 | Alias Symbol: TRIM49A | ||
| Type: protein-coding gene | Cytoband: 11p11.12-q12 | ||
| Entrez ID: 57093 | HGNC ID: HGNC:13431 | Ensembl Gene: ENSG00000168930 | OMIM ID: 606124 |
| Drug and gene relationship at DGIdb | |||
Expression of TRIM49:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | TRIM49 | 57093 | 53690 | 0.3562 | 0.0397 | |
| GSE53624 | TRIM49 | 57093 | 53690 | 0.3188 | 0.0055 | |
| GSE97050 | TRIM49 | 57093 | A_23_P1575 | -0.1677 | 0.6268 | |
| TCGA | TRIM49 | 57093 | RNAseq | 1.2252 | 0.4651 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TRIM49 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRIM49:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRIM49 | 57093 | 3 | 10 | 17 | |
| GSE20123 | TRIM49 | 57093 | 3 | 10 | 17 | |
| GSE43470 | TRIM49 | 57093 | 3 | 4 | 36 | |
| GSE46452 | TRIM49 | 57093 | 6 | 23 | 30 | |
| GSE47630 | TRIM49 | 57093 | 2 | 19 | 19 | |
| GSE54993 | TRIM49 | 57093 | 8 | 2 | 60 | |
| GSE54994 | TRIM49 | 57093 | 5 | 19 | 29 | |
| GSE60625 | TRIM49 | 57093 | 0 | 3 | 8 | |
| GSE74703 | TRIM49 | 57093 | 2 | 3 | 31 | |
| GSE74704 | TRIM49 | 57093 | 3 | 6 | 11 | |
| TCGA | TRIM49 | 57093 | 15 | 39 | 42 |
Total number of gains: 50; Total number of losses: 138; Total Number of normals: 300.
Somatic mutations of TRIM49:
Generating mutation plots.
Highly correlated genes for TRIM49:
Showing all 14 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRIM49 | TRIM43 | 0.835934 | 3 | 0 | 3 |
| TRIM49 | PRAMEF5 | 0.811194 | 3 | 0 | 3 |
| TRIM49 | OR4A15 | 0.792297 | 3 | 0 | 3 |
| TRIM49 | OR2D2 | 0.751264 | 3 | 0 | 3 |
| TRIM49 | OR4D1 | 0.745487 | 3 | 0 | 3 |
| TRIM49 | OR4F21 | 0.734268 | 3 | 0 | 3 |
| TRIM49 | CLEC1B | 0.730576 | 3 | 0 | 3 |
| TRIM49 | PNMA3 | 0.711864 | 3 | 0 | 3 |
| TRIM49 | USP51 | 0.699606 | 3 | 0 | 3 |
| TRIM49 | OR7G2 | 0.699082 | 3 | 0 | 3 |
| TRIM49 | GOLGA6L6 | 0.683564 | 3 | 0 | 3 |
| TRIM49 | OR1F1 | 0.682869 | 3 | 0 | 3 |
| TRIM49 | SLCO1A2 | 0.645426 | 3 | 0 | 3 |
| TRIM49 | OTOG | 0.639491 | 3 | 0 | 3 |
For details and further investigation, click here
