| Full name: PRAME family member 5 | Alias Symbol: PRAMEF5L | ||
| Type: protein-coding gene | Cytoband: 1p36.21 | ||
| Entrez ID: 343068 | HGNC ID: HGNC:27995 | Ensembl Gene: ENSG00000270601 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PRAMEF5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | PRAMEF5 | 343068 | 138144 | 0.3808 | 0.0396 | |
| GSE53624 | PRAMEF5 | 343068 | 138144 | 0.2941 | 0.0067 | |
| GSE97050 | PRAMEF5 | 343068 | A_33_P3309911 | 0.0111 | 0.9740 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PRAMEF5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRAMEF5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRAMEF5 | 343068 | 0 | 4 | 26 | |
| GSE20123 | PRAMEF5 | 343068 | 0 | 3 | 27 | |
| GSE43470 | PRAMEF5 | 343068 | 2 | 6 | 35 | |
| GSE46452 | PRAMEF5 | 343068 | 7 | 1 | 51 | |
| GSE47630 | PRAMEF5 | 343068 | 8 | 3 | 29 | |
| GSE54993 | PRAMEF5 | 343068 | 3 | 1 | 66 | |
| GSE54994 | PRAMEF5 | 343068 | 11 | 4 | 38 | |
| GSE60625 | PRAMEF5 | 343068 | 0 | 0 | 11 | |
| GSE74703 | PRAMEF5 | 343068 | 2 | 4 | 30 | |
| GSE74704 | PRAMEF5 | 343068 | 0 | 0 | 20 | |
| TCGA | PRAMEF5 | 343068 | 10 | 22 | 64 |
Total number of gains: 43; Total number of losses: 48; Total Number of normals: 397.
Somatic mutations of PRAMEF5:
Generating mutation plots.
Highly correlated genes for PRAMEF5:
Showing top 20/145 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRAMEF5 | TRIM49 | 0.811194 | 3 | 0 | 3 |
| PRAMEF5 | FAM71F1 | 0.810092 | 3 | 0 | 3 |
| PRAMEF5 | OR2D2 | 0.79653 | 3 | 0 | 3 |
| PRAMEF5 | TRIM43 | 0.785971 | 3 | 0 | 3 |
| PRAMEF5 | TTLL9 | 0.779059 | 3 | 0 | 3 |
| PRAMEF5 | OPN4 | 0.771878 | 3 | 0 | 3 |
| PRAMEF5 | ANGPT4 | 0.769998 | 3 | 0 | 3 |
| PRAMEF5 | ROM1 | 0.763353 | 3 | 0 | 3 |
| PRAMEF5 | DEFB121 | 0.762992 | 3 | 0 | 3 |
| PRAMEF5 | KRTAP10-12 | 0.759695 | 3 | 0 | 3 |
| PRAMEF5 | BAALC | 0.756384 | 3 | 0 | 3 |
| PRAMEF5 | SLC26A1 | 0.753397 | 3 | 0 | 3 |
| PRAMEF5 | MEP1A | 0.750742 | 3 | 0 | 3 |
| PRAMEF5 | CLEC1B | 0.750671 | 3 | 0 | 3 |
| PRAMEF5 | PNMA3 | 0.747129 | 3 | 0 | 3 |
| PRAMEF5 | TMEM105 | 0.744982 | 3 | 0 | 3 |
| PRAMEF5 | KRTAP4-8 | 0.744342 | 3 | 0 | 3 |
| PRAMEF5 | ZNF763 | 0.744209 | 3 | 0 | 3 |
| PRAMEF5 | SLC22A11 | 0.743198 | 3 | 0 | 3 |
| PRAMEF5 | XRCC2 | 0.742582 | 3 | 0 | 3 |
For details and further investigation, click here
