| Full name: olfactory receptor family 4 subfamily F member 21 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8p23.3 | ||
| Entrez ID: 441308 | HGNC ID: HGNC:19583 | Ensembl Gene: ENSG00000176269 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
OR4F21 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04740 | Olfactory transduction |
Expression of OR4F21:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | OR4F21 | 441308 | 38523 | 0.3619 | 0.0024 | |
| GSE53624 | OR4F21 | 441308 | 38523 | 0.3714 | 0.0000 | |
| GSE97050 | OR4F21 | 441308 | A_33_P3316147 | 0.0427 | 0.8979 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OR4F21 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OR4F21:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OR4F21 | 441308 | 6 | 12 | 12 | |
| GSE20123 | OR4F21 | 441308 | 6 | 12 | 12 | |
| GSE43470 | OR4F21 | 441308 | 5 | 8 | 30 | |
| GSE46452 | OR4F21 | 441308 | 12 | 14 | 33 | |
| GSE47630 | OR4F21 | 441308 | 9 | 8 | 23 | |
| GSE54993 | OR4F21 | 441308 | 5 | 14 | 51 | |
| GSE54994 | OR4F21 | 441308 | 9 | 18 | 26 | |
| GSE60625 | OR4F21 | 441308 | 3 | 0 | 8 | |
| GSE74703 | OR4F21 | 441308 | 5 | 6 | 25 | |
| GSE74704 | OR4F21 | 441308 | 5 | 7 | 8 | |
| TCGA | OR4F21 | 441308 | 16 | 40 | 40 |
Total number of gains: 81; Total number of losses: 139; Total Number of normals: 268.
Somatic mutations of OR4F21:
Generating mutation plots.
Highly correlated genes for OR4F21:
Showing top 20/56 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OR4F21 | OR7G2 | 0.756216 | 3 | 0 | 3 |
| OR4F21 | OR4D1 | 0.741576 | 3 | 0 | 3 |
| OR4F21 | TRIM49 | 0.734268 | 3 | 0 | 3 |
| OR4F21 | MEP1A | 0.731259 | 3 | 0 | 3 |
| OR4F21 | OR2A5 | 0.724455 | 3 | 0 | 3 |
| OR4F21 | CRYGC | 0.724154 | 3 | 0 | 3 |
| OR4F21 | TTLL9 | 0.722912 | 3 | 0 | 3 |
| OR4F21 | OR2D2 | 0.715573 | 3 | 0 | 3 |
| OR4F21 | OR2T4 | 0.713708 | 3 | 0 | 3 |
| OR4F21 | DEFB121 | 0.713202 | 3 | 0 | 3 |
| OR4F21 | DRGX | 0.709267 | 3 | 0 | 3 |
| OR4F21 | AANAT | 0.706713 | 3 | 0 | 3 |
| OR4F21 | FAM71F1 | 0.703887 | 3 | 0 | 3 |
| OR4F21 | DGKZ | 0.702919 | 3 | 0 | 3 |
| OR4F21 | TAS2R30 | 0.695359 | 3 | 0 | 3 |
| OR4F21 | SERPINA10 | 0.69295 | 3 | 0 | 3 |
| OR4F21 | OR56A5 | 0.688945 | 3 | 0 | 3 |
| OR4F21 | MAGEL2 | 0.687509 | 3 | 0 | 3 |
| OR4F21 | PRAMEF5 | 0.687047 | 4 | 0 | 3 |
| OR4F21 | PNMA3 | 0.685813 | 3 | 0 | 3 |
For details and further investigation, click here
