| Full name: otogelin | Alias Symbol: mlemp|OTGN|FLJ46346 | ||
| Type: protein-coding gene | Cytoband: 11p15.1 | ||
| Entrez ID: 340990 | HGNC ID: HGNC:8516 | Ensembl Gene: ENSG00000188162 | OMIM ID: 604487 |
| Drug and gene relationship at DGIdb | |||
Expression of OTOG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | OTOG | 340990 | 100857 | -0.1079 | 0.1630 | |
| GSE53624 | OTOG | 340990 | 100857 | -0.0747 | 0.4336 | |
| GSE97050 | OTOG | 340990 | A_33_P3326643 | -0.1097 | 0.7743 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OTOG expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of OTOG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OTOG | 340990 | 0 | 10 | 20 | |
| GSE20123 | OTOG | 340990 | 0 | 10 | 20 | |
| GSE43470 | OTOG | 340990 | 1 | 5 | 37 | |
| GSE46452 | OTOG | 340990 | 7 | 5 | 47 | |
| GSE47630 | OTOG | 340990 | 3 | 10 | 27 | |
| GSE54993 | OTOG | 340990 | 3 | 0 | 67 | |
| GSE54994 | OTOG | 340990 | 3 | 12 | 38 | |
| GSE60625 | OTOG | 340990 | 0 | 0 | 11 | |
| GSE74703 | OTOG | 340990 | 1 | 3 | 32 | |
| GSE74704 | OTOG | 340990 | 0 | 9 | 11 | |
| TCGA | OTOG | 340990 | 11 | 29 | 56 |
Total number of gains: 29; Total number of losses: 93; Total Number of normals: 366.
Somatic mutations of OTOG:
Generating mutation plots.
Highly correlated genes for OTOG:
Showing top 20/279 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OTOG | SLC22A12 | 0.842485 | 3 | 0 | 3 |
| OTOG | INSC | 0.83964 | 3 | 0 | 3 |
| OTOG | YY2 | 0.832207 | 3 | 0 | 3 |
| OTOG | KCNQ4 | 0.819083 | 3 | 0 | 3 |
| OTOG | PRSS38 | 0.816506 | 3 | 0 | 3 |
| OTOG | WDR87 | 0.816061 | 3 | 0 | 3 |
| OTOG | PDZRN3 | 0.815844 | 3 | 0 | 3 |
| OTOG | TXNDC2 | 0.814308 | 3 | 0 | 3 |
| OTOG | SIM1 | 0.814172 | 3 | 0 | 3 |
| OTOG | KRTAP4-8 | 0.814002 | 3 | 0 | 3 |
| OTOG | PAX6 | 0.813075 | 3 | 0 | 3 |
| OTOG | KRTAP10-12 | 0.812361 | 3 | 0 | 3 |
| OTOG | OPN4 | 0.812143 | 3 | 0 | 3 |
| OTOG | TTC21A | 0.810622 | 3 | 0 | 3 |
| OTOG | OR10AD1 | 0.810328 | 3 | 0 | 3 |
| OTOG | AANAT | 0.808817 | 3 | 0 | 3 |
| OTOG | OR1F1 | 0.808237 | 3 | 0 | 3 |
| OTOG | KCNJ13 | 0.804578 | 3 | 0 | 3 |
| OTOG | INSL3 | 0.804133 | 3 | 0 | 3 |
| OTOG | SLC26A1 | 0.803147 | 3 | 0 | 3 |
For details and further investigation, click here
