| Full name: tripartite motif containing 43 | Alias Symbol: TRIM43A | ||
| Type: protein-coding gene | Cytoband: 2q11.1 | ||
| Entrez ID: 129868 | HGNC ID: HGNC:19015 | Ensembl Gene: ENSG00000144015 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of TRIM43:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | TRIM43 | 129868 | 3347 | 0.1165 | 0.6058 | |
| GSE53624 | TRIM43 | 129868 | 3347 | 0.4803 | 0.0001 | |
| GSE97050 | TRIM43 | 129868 | A_33_P3248163 | 0.1780 | 0.4692 | |
| TCGA | TRIM43 | 129868 | RNAseq | 1.1126 | 0.6843 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TRIM43 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRIM43:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRIM43 | 129868 | 6 | 2 | 22 | |
| GSE20123 | TRIM43 | 129868 | 6 | 2 | 22 | |
| GSE43470 | TRIM43 | 129868 | 3 | 2 | 38 | |
| GSE46452 | TRIM43 | 129868 | 2 | 3 | 54 | |
| GSE47630 | TRIM43 | 129868 | 7 | 0 | 33 | |
| GSE54993 | TRIM43 | 129868 | 0 | 6 | 64 | |
| GSE54994 | TRIM43 | 129868 | 11 | 0 | 42 | |
| GSE60625 | TRIM43 | 129868 | 0 | 3 | 8 | |
| GSE74703 | TRIM43 | 129868 | 3 | 1 | 32 | |
| GSE74704 | TRIM43 | 129868 | 4 | 1 | 15 | |
| TCGA | TRIM43 | 129868 | 35 | 4 | 57 |
Total number of gains: 77; Total number of losses: 24; Total Number of normals: 387.
Somatic mutations of TRIM43:
Generating mutation plots.
Highly correlated genes for TRIM43:
Showing top 20/34 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRIM43 | TRIM49 | 0.835934 | 3 | 0 | 3 |
| TRIM43 | OR4A15 | 0.828763 | 3 | 0 | 3 |
| TRIM43 | OR4D1 | 0.812066 | 3 | 0 | 3 |
| TRIM43 | OR2D2 | 0.804341 | 3 | 0 | 3 |
| TRIM43 | PRAMEF5 | 0.785971 | 3 | 0 | 3 |
| TRIM43 | OR56A5 | 0.76048 | 3 | 0 | 3 |
| TRIM43 | GLYATL1 | 0.756151 | 3 | 0 | 3 |
| TRIM43 | SPTA1 | 0.752252 | 4 | 0 | 4 |
| TRIM43 | TRIM10 | 0.741924 | 3 | 0 | 3 |
| TRIM43 | MEP1A | 0.740201 | 3 | 0 | 3 |
| TRIM43 | ACRV1 | 0.736395 | 3 | 0 | 3 |
| TRIM43 | LYZL2 | 0.726985 | 3 | 0 | 3 |
| TRIM43 | CPNE9 | 0.717054 | 3 | 0 | 3 |
| TRIM43 | CLEC1B | 0.711795 | 3 | 0 | 3 |
| TRIM43 | AANAT | 0.707503 | 3 | 0 | 3 |
| TRIM43 | TNFSF11 | 0.703428 | 3 | 0 | 3 |
| TRIM43 | OR7G2 | 0.701325 | 3 | 0 | 3 |
| TRIM43 | CLTCL1 | 0.700791 | 3 | 0 | 3 |
| TRIM43 | MMP19 | 0.699117 | 3 | 0 | 3 |
| TRIM43 | GJD4 | 0.696823 | 3 | 0 | 3 |
For details and further investigation, click here
