TXNDC8

 

Full name: thioredoxin domain containing 8 Alias Symbol: bA427L11.2|TRX6|SPTRX-3
Type: protein-coding gene Cytoband: 9q31.3
Entrez ID: 255220 HGNC ID: HGNC:31454 Ensembl Gene: ENSG00000204193 OMIM ID: 617789

 

Expression of TXNDC8:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TXNDC8 255220 1564386_at 0.0558 0.8240
GSE26886 TXNDC8 255220 1564386_at -0.1608 0.1273
GSE45670 TXNDC8 255220 1564386_at 0.0211 0.8121
GSE53622 TXNDC8 255220 7743 0.6023 0.0000
GSE53624 TXNDC8 255220 7743 0.9236 0.0000
GSE63941 TXNDC8 255220 1564386_at -0.1509 0.3107
GSE77861 TXNDC8 255220 1564386_at -0.0441 0.6145

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by TXNDC8 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TXNDC8:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TXNDC8 255220 5 10 15
GSE20123 TXNDC8 255220 5 9 16
GSE43470 TXNDC8 255220 4 3 36
GSE46452 TXNDC8 255220 6 13 40
GSE47630 TXNDC8 255220 3 16 21
GSE54993 TXNDC8 255220 3 3 64
GSE54994 TXNDC8 255220 9 10 34
GSE60625 TXNDC8 255220 0 0 11
GSE74703 TXNDC8 255220 4 3 29
GSE74704 TXNDC8 255220 2 6 12
TCGA TXNDC8 255220 25 22 49

Total number of gains: 66; Total number of losses: 95; Total Number of normals: 327.  

 

Somatic mutations of TXNDC8:

 

Generating mutation plots.

 

Highly correlated genes for TXNDC8:

 

Showing all 7 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TXNDC8IGFBP10.584732303
TXNDC8SMAD20.567801303
TXNDC8ZBTB140.550329303
TXNDC8JRK0.549708403
TXNDC8ZNRF40.536719403
TXNDC8TCAP0.512604403
TXNDC8CLECL10.50706403

For details and further investigation, click here