| Full name: zinc and ring finger 4 | Alias Symbol: spzn|Ssrzf1|RNF204 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 148066 | HGNC ID: HGNC:17726 | Ensembl Gene: ENSG00000105428 | OMIM ID: 612063 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNRF4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNRF4 | 148066 | 215461_at | 0.1295 | 0.6249 | |
| GSE20347 | ZNRF4 | 148066 | 215461_at | 0.0254 | 0.8075 | |
| GSE23400 | ZNRF4 | 148066 | 215461_at | -0.0613 | 0.0547 | |
| GSE26886 | ZNRF4 | 148066 | 215461_at | 0.1796 | 0.1592 | |
| GSE29001 | ZNRF4 | 148066 | 215461_at | -0.0750 | 0.5356 | |
| GSE38129 | ZNRF4 | 148066 | 215461_at | -0.0273 | 0.6574 | |
| GSE45670 | ZNRF4 | 148066 | 215461_at | 0.0871 | 0.2420 | |
| GSE53622 | ZNRF4 | 148066 | 23021 | 0.7023 | 0.0000 | |
| GSE53624 | ZNRF4 | 148066 | 23021 | 0.9601 | 0.0000 | |
| GSE63941 | ZNRF4 | 148066 | 215461_at | 0.2481 | 0.1185 | |
| GSE77861 | ZNRF4 | 148066 | 215461_at | -0.0597 | 0.5906 | |
| GSE97050 | ZNRF4 | 148066 | A_23_P374559 | 0.7202 | 0.1992 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNRF4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNRF4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNRF4 | 148066 | 5 | 3 | 22 | |
| GSE20123 | ZNRF4 | 148066 | 4 | 2 | 24 | |
| GSE43470 | ZNRF4 | 148066 | 2 | 6 | 35 | |
| GSE46452 | ZNRF4 | 148066 | 47 | 1 | 11 | |
| GSE47630 | ZNRF4 | 148066 | 5 | 7 | 28 | |
| GSE54993 | ZNRF4 | 148066 | 16 | 3 | 51 | |
| GSE54994 | ZNRF4 | 148066 | 6 | 16 | 31 | |
| GSE60625 | ZNRF4 | 148066 | 9 | 0 | 2 | |
| GSE74703 | ZNRF4 | 148066 | 2 | 4 | 30 | |
| GSE74704 | ZNRF4 | 148066 | 1 | 2 | 17 | |
| TCGA | ZNRF4 | 148066 | 12 | 18 | 66 |
Total number of gains: 109; Total number of losses: 62; Total Number of normals: 317.
Somatic mutations of ZNRF4:
Generating mutation plots.
Highly correlated genes for ZNRF4:
Showing top 20/739 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNRF4 | C2CD4D | 0.736615 | 3 | 0 | 3 |
| ZNRF4 | RFX8 | 0.73128 | 3 | 0 | 3 |
| ZNRF4 | SLC6A13 | 0.731271 | 3 | 0 | 3 |
| ZNRF4 | MATN1 | 0.712079 | 3 | 0 | 3 |
| ZNRF4 | ART1 | 0.710605 | 3 | 0 | 3 |
| ZNRF4 | TBX21 | 0.709829 | 5 | 0 | 4 |
| ZNRF4 | PRLH | 0.706382 | 6 | 0 | 6 |
| ZNRF4 | ATXN7L2 | 0.702184 | 3 | 0 | 3 |
| ZNRF4 | MRGPRG | 0.700496 | 3 | 0 | 3 |
| ZNRF4 | OPRD1 | 0.699993 | 7 | 0 | 7 |
| ZNRF4 | OPTC | 0.699219 | 5 | 0 | 4 |
| ZNRF4 | FUZ | 0.697556 | 3 | 0 | 3 |
| ZNRF4 | NTNG2 | 0.696163 | 4 | 0 | 4 |
| ZNRF4 | HOXB6 | 0.695231 | 3 | 0 | 3 |
| ZNRF4 | FBLN7 | 0.692404 | 3 | 0 | 3 |
| ZNRF4 | CDK16 | 0.688973 | 3 | 0 | 3 |
| ZNRF4 | KIFC2 | 0.687792 | 3 | 0 | 3 |
| ZNRF4 | SLC6A3 | 0.685825 | 6 | 0 | 5 |
| ZNRF4 | CEACAM20 | 0.676928 | 3 | 0 | 3 |
| ZNRF4 | LIM2 | 0.676391 | 4 | 0 | 4 |
For details and further investigation, click here
