| Full name: Jrk helix-turn-helix protein | Alias Symbol: JH8|jerky | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 8629 | HGNC ID: HGNC:6199 | Ensembl Gene: ENSG00000234616 | OMIM ID: 603210 |
| Drug and gene relationship at DGIdb | |||
Expression of JRK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | JRK | 8629 | 214692_s_at | 0.5912 | 0.2038 | |
| GSE20347 | JRK | 8629 | 216309_x_at | 0.3663 | 0.0088 | |
| GSE23400 | JRK | 8629 | 216309_x_at | 0.1350 | 0.0054 | |
| GSE26886 | JRK | 8629 | 216309_x_at | -0.1560 | 0.1420 | |
| GSE29001 | JRK | 8629 | 216309_x_at | 0.1805 | 0.4395 | |
| GSE38129 | JRK | 8629 | 216309_x_at | 0.1010 | 0.5874 | |
| GSE45670 | JRK | 8629 | 216309_x_at | 0.3247 | 0.0051 | |
| GSE53622 | JRK | 8629 | 2334 | 0.6594 | 0.0000 | |
| GSE53624 | JRK | 8629 | 2334 | 0.6597 | 0.0000 | |
| GSE63941 | JRK | 8629 | 216309_x_at | 0.9179 | 0.0067 | |
| GSE77861 | JRK | 8629 | 37872_at | -0.0983 | 0.3595 | |
| GSE97050 | JRK | 8629 | A_33_P3275199 | -0.0110 | 0.9762 | |
| SRP007169 | JRK | 8629 | RNAseq | -0.4944 | 0.2363 | |
| SRP008496 | JRK | 8629 | RNAseq | -0.7857 | 0.0229 | |
| SRP064894 | JRK | 8629 | RNAseq | 0.2600 | 0.2737 | |
| SRP133303 | JRK | 8629 | RNAseq | -0.0970 | 0.3654 | |
| SRP159526 | JRK | 8629 | RNAseq | -0.0391 | 0.8932 | |
| SRP193095 | JRK | 8629 | RNAseq | 0.0887 | 0.4589 | |
| SRP219564 | JRK | 8629 | RNAseq | 0.4353 | 0.3783 | |
| TCGA | JRK | 8629 | RNAseq | -0.1161 | 0.0869 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by JRK expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of JRK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | JRK | 8629 | 16 | 1 | 13 | |
| GSE20123 | JRK | 8629 | 17 | 1 | 12 | |
| GSE43470 | JRK | 8629 | 17 | 2 | 24 | |
| GSE46452 | JRK | 8629 | 27 | 0 | 32 | |
| GSE47630 | JRK | 8629 | 23 | 1 | 16 | |
| GSE54993 | JRK | 8629 | 0 | 25 | 45 | |
| GSE54994 | JRK | 8629 | 39 | 1 | 13 | |
| GSE60625 | JRK | 8629 | 3 | 4 | 4 | |
| GSE74703 | JRK | 8629 | 15 | 1 | 20 | |
| GSE74704 | JRK | 8629 | 10 | 0 | 10 | |
| TCGA | JRK | 8629 | 63 | 2 | 31 |
Total number of gains: 230; Total number of losses: 38; Total Number of normals: 220.
Somatic mutations of JRK:
Generating mutation plots.
Highly correlated genes for JRK:
Showing top 20/379 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| JRK | MAF1 | 0.740807 | 3 | 0 | 3 |
| JRK | TMEM235 | 0.736832 | 3 | 0 | 3 |
| JRK | TSPAN16 | 0.729764 | 3 | 0 | 3 |
| JRK | USP2-AS1 | 0.724762 | 3 | 0 | 3 |
| JRK | C9orf153 | 0.720194 | 3 | 0 | 3 |
| JRK | LAT2 | 0.720068 | 4 | 0 | 4 |
| JRK | C1orf35 | 0.709982 | 4 | 0 | 4 |
| JRK | SPRED3 | 0.708699 | 4 | 0 | 4 |
| JRK | ST14 | 0.707966 | 3 | 0 | 3 |
| JRK | ST8SIA3 | 0.694399 | 4 | 0 | 4 |
| JRK | LBX2 | 0.691839 | 3 | 0 | 3 |
| JRK | TIGD5 | 0.681638 | 4 | 0 | 4 |
| JRK | HAGHL | 0.68051 | 3 | 0 | 3 |
| JRK | POU4F1 | 0.678305 | 3 | 0 | 3 |
| JRK | MRGPRG | 0.677437 | 3 | 0 | 3 |
| JRK | EMC10 | 0.675819 | 3 | 0 | 3 |
| JRK | BIN3-IT1 | 0.674485 | 3 | 0 | 3 |
| JRK | TEX35 | 0.66803 | 4 | 0 | 4 |
| JRK | KRTAP10-12 | 0.66721 | 3 | 0 | 3 |
| JRK | GHSR | 0.661692 | 4 | 0 | 3 |
For details and further investigation, click here
