| Full name: unc-13 homolog C | Alias Symbol: Munc13-3|DKFZp547H074 | ||
| Type: protein-coding gene | Cytoband: 15q21.3 | ||
| Entrez ID: 440279 | HGNC ID: HGNC:23149 | Ensembl Gene: ENSG00000137766 | OMIM ID: 614568 |
| Drug and gene relationship at DGIdb | |||
Expression of UNC13C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UNC13C | 440279 | 1562074_a_at | 0.0663 | 0.8278 | |
| GSE26886 | UNC13C | 440279 | 1562074_a_at | 0.0261 | 0.8256 | |
| GSE45670 | UNC13C | 440279 | 1562074_a_at | 0.0282 | 0.7400 | |
| GSE53622 | UNC13C | 440279 | 5547 | -0.0482 | 0.7796 | |
| GSE53624 | UNC13C | 440279 | 5547 | -0.4061 | 0.0027 | |
| GSE63941 | UNC13C | 440279 | 1562074_a_at | 0.1160 | 0.4056 | |
| GSE77861 | UNC13C | 440279 | 1562074_a_at | 0.0149 | 0.8923 | |
| SRP007169 | UNC13C | 440279 | RNAseq | -0.2658 | 0.7059 | |
| SRP064894 | UNC13C | 440279 | RNAseq | 0.2437 | 0.3489 | |
| SRP133303 | UNC13C | 440279 | RNAseq | -0.0964 | 0.4595 | |
| SRP159526 | UNC13C | 440279 | RNAseq | -0.0901 | 0.8634 | |
| SRP193095 | UNC13C | 440279 | RNAseq | -0.0471 | 0.7633 | |
| SRP219564 | UNC13C | 440279 | RNAseq | 0.2756 | 0.6141 | |
| TCGA | UNC13C | 440279 | RNAseq | -2.6522 | 0.0095 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by UNC13C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UNC13C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UNC13C | 440279 | 5 | 3 | 22 | |
| GSE20123 | UNC13C | 440279 | 5 | 3 | 22 | |
| GSE43470 | UNC13C | 440279 | 4 | 1 | 38 | |
| GSE46452 | UNC13C | 440279 | 3 | 7 | 49 | |
| GSE47630 | UNC13C | 440279 | 8 | 10 | 22 | |
| GSE54993 | UNC13C | 440279 | 5 | 6 | 59 | |
| GSE54994 | UNC13C | 440279 | 5 | 8 | 40 | |
| GSE60625 | UNC13C | 440279 | 4 | 0 | 7 | |
| GSE74703 | UNC13C | 440279 | 4 | 1 | 31 | |
| GSE74704 | UNC13C | 440279 | 1 | 3 | 16 | |
| TCGA | UNC13C | 440279 | 10 | 16 | 70 |
Total number of gains: 54; Total number of losses: 58; Total Number of normals: 376.
Somatic mutations of UNC13C:
Generating mutation plots.
Highly correlated genes for UNC13C:
Showing all 12 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UNC13C | BPIFB6 | 0.622455 | 3 | 0 | 3 |
| UNC13C | GFRA4 | 0.603159 | 3 | 0 | 3 |
| UNC13C | PRODH2 | 0.588559 | 3 | 0 | 3 |
| UNC13C | OR51B2 | 0.580151 | 3 | 0 | 3 |
| UNC13C | SNAP25 | 0.569185 | 4 | 0 | 3 |
| UNC13C | SUN5 | 0.558713 | 4 | 0 | 3 |
| UNC13C | MYRFL | 0.544487 | 3 | 0 | 3 |
| UNC13C | LINC00937 | 0.539411 | 3 | 0 | 3 |
| UNC13C | OSM | 0.538102 | 4 | 0 | 3 |
| UNC13C | LTK | 0.532386 | 4 | 0 | 3 |
| UNC13C | CCL4 | 0.514912 | 3 | 0 | 3 |
| UNC13C | WWTR1-AS1 | 0.505759 | 4 | 0 | 3 |
For details and further investigation, click here
