| Full name: proline dehydrogenase 2 | Alias Symbol: HSPOX1 | ||
| Type: protein-coding gene | Cytoband: 19q13.12 | ||
| Entrez ID: 58510 | HGNC ID: HGNC:17325 | Ensembl Gene: ENSG00000250799 | OMIM ID: 616377 |
| Drug and gene relationship at DGIdb | |||
Expression of PRODH2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRODH2 | 58510 | 216696_s_at | -0.1265 | 0.6611 | |
| GSE20347 | PRODH2 | 58510 | 216696_s_at | 0.0233 | 0.8331 | |
| GSE23400 | PRODH2 | 58510 | 216696_s_at | -0.0988 | 0.0082 | |
| GSE26886 | PRODH2 | 58510 | 216696_s_at | 0.0319 | 0.8432 | |
| GSE29001 | PRODH2 | 58510 | 216696_s_at | -0.1420 | 0.4646 | |
| GSE38129 | PRODH2 | 58510 | 216696_s_at | -0.2118 | 0.0173 | |
| GSE45670 | PRODH2 | 58510 | 216696_s_at | 0.0693 | 0.3340 | |
| GSE53622 | PRODH2 | 58510 | 4130 | 0.3349 | 0.0000 | |
| GSE53624 | PRODH2 | 58510 | 4130 | 0.2741 | 0.0004 | |
| GSE63941 | PRODH2 | 58510 | 216696_s_at | 0.1786 | 0.2010 | |
| GSE77861 | PRODH2 | 58510 | 216696_s_at | 0.0045 | 0.9661 | |
| GSE97050 | PRODH2 | 58510 | A_23_P165201 | -0.0297 | 0.9029 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PRODH2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRODH2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRODH2 | 58510 | 7 | 4 | 19 | |
| GSE20123 | PRODH2 | 58510 | 7 | 3 | 20 | |
| GSE43470 | PRODH2 | 58510 | 3 | 7 | 33 | |
| GSE46452 | PRODH2 | 58510 | 48 | 1 | 10 | |
| GSE47630 | PRODH2 | 58510 | 9 | 5 | 26 | |
| GSE54993 | PRODH2 | 58510 | 17 | 3 | 50 | |
| GSE54994 | PRODH2 | 58510 | 6 | 9 | 38 | |
| GSE60625 | PRODH2 | 58510 | 9 | 0 | 2 | |
| GSE74703 | PRODH2 | 58510 | 3 | 4 | 29 | |
| GSE74704 | PRODH2 | 58510 | 6 | 1 | 13 | |
| TCGA | PRODH2 | 58510 | 22 | 10 | 64 |
Total number of gains: 137; Total number of losses: 47; Total Number of normals: 304.
Somatic mutations of PRODH2:
Generating mutation plots.
Highly correlated genes for PRODH2:
Showing top 20/1288 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRODH2 | OR10W1 | 0.823511 | 3 | 0 | 3 |
| PRODH2 | C22orf23 | 0.80846 | 3 | 0 | 3 |
| PRODH2 | OR2G2 | 0.791687 | 3 | 0 | 3 |
| PRODH2 | OR2D3 | 0.784976 | 3 | 0 | 3 |
| PRODH2 | FZD9 | 0.769302 | 3 | 0 | 3 |
| PRODH2 | ERN1 | 0.755924 | 4 | 0 | 4 |
| PRODH2 | OR4C6 | 0.755026 | 3 | 0 | 3 |
| PRODH2 | FOXN3-AS2 | 0.751195 | 5 | 0 | 5 |
| PRODH2 | PRKAR1B | 0.750323 | 4 | 0 | 3 |
| PRODH2 | TLR8 | 0.725873 | 3 | 0 | 3 |
| PRODH2 | FSCN3 | 0.723617 | 6 | 0 | 5 |
| PRODH2 | KIR3DL3 | 0.722527 | 6 | 0 | 5 |
| PRODH2 | SGK2 | 0.721406 | 6 | 0 | 6 |
| PRODH2 | ARPP21 | 0.719633 | 4 | 0 | 4 |
| PRODH2 | B3GAT3 | 0.717807 | 3 | 0 | 3 |
| PRODH2 | MS4A18 | 0.716572 | 3 | 0 | 3 |
| PRODH2 | ALDH8A1 | 0.714585 | 3 | 0 | 3 |
| PRODH2 | MMP19 | 0.714324 | 6 | 0 | 5 |
| PRODH2 | CHTF8 | 0.713848 | 3 | 0 | 3 |
| PRODH2 | SRPK3 | 0.713753 | 7 | 0 | 7 |
For details and further investigation, click here
