| Full name: GDNF family receptor alpha 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 64096 | HGNC ID: HGNC:13821 | Ensembl Gene: ENSG00000125861 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of GFRA4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GFRA4 | 64096 | 221199_at | 0.0615 | 0.8605 | |
| GSE20347 | GFRA4 | 64096 | 221199_at | 0.0110 | 0.9217 | |
| GSE23400 | GFRA4 | 64096 | 221199_at | -0.1710 | 0.0002 | |
| GSE26886 | GFRA4 | 64096 | 234868_s_at | 0.1680 | 0.1200 | |
| GSE29001 | GFRA4 | 64096 | 221199_at | -0.2230 | 0.0795 | |
| GSE38129 | GFRA4 | 64096 | 221199_at | -0.0523 | 0.6183 | |
| GSE45670 | GFRA4 | 64096 | 221199_at | 0.0619 | 0.6132 | |
| GSE53622 | GFRA4 | 64096 | 133172 | 0.1499 | 0.1084 | |
| GSE53624 | GFRA4 | 64096 | 133172 | -0.0385 | 0.7403 | |
| GSE63941 | GFRA4 | 64096 | 221199_at | 0.0709 | 0.6345 | |
| GSE77861 | GFRA4 | 64096 | 221199_at | 0.0105 | 0.9537 | |
| GSE97050 | GFRA4 | 64096 | A_33_P3317589 | 0.1546 | 0.5357 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GFRA4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GFRA4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GFRA4 | 64096 | 12 | 3 | 15 | |
| GSE20123 | GFRA4 | 64096 | 13 | 3 | 14 | |
| GSE43470 | GFRA4 | 64096 | 10 | 1 | 32 | |
| GSE46452 | GFRA4 | 64096 | 26 | 1 | 32 | |
| GSE47630 | GFRA4 | 64096 | 18 | 4 | 18 | |
| GSE54993 | GFRA4 | 64096 | 2 | 14 | 54 | |
| GSE54994 | GFRA4 | 64096 | 24 | 2 | 27 | |
| GSE60625 | GFRA4 | 64096 | 0 | 0 | 11 | |
| GSE74703 | GFRA4 | 64096 | 9 | 1 | 26 | |
| GSE74704 | GFRA4 | 64096 | 8 | 1 | 11 | |
| TCGA | GFRA4 | 64096 | 39 | 11 | 46 |
Total number of gains: 161; Total number of losses: 41; Total Number of normals: 286.
Somatic mutations of GFRA4:
Generating mutation plots.
Highly correlated genes for GFRA4:
Showing top 20/1213 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GFRA4 | STRC | 0.870169 | 3 | 0 | 3 |
| GFRA4 | ANKDD1A | 0.853727 | 3 | 0 | 3 |
| GFRA4 | CELF5 | 0.82626 | 3 | 0 | 3 |
| GFRA4 | FAM71A | 0.815588 | 3 | 0 | 3 |
| GFRA4 | OR4D6 | 0.795627 | 3 | 0 | 3 |
| GFRA4 | PLA2G2C | 0.786846 | 3 | 0 | 3 |
| GFRA4 | PRAP1 | 0.777909 | 3 | 0 | 3 |
| GFRA4 | RHBDL1 | 0.771317 | 3 | 0 | 3 |
| GFRA4 | PNPLA7 | 0.76365 | 3 | 0 | 3 |
| GFRA4 | DCDC1 | 0.761936 | 3 | 0 | 3 |
| GFRA4 | IL1F10 | 0.761743 | 4 | 0 | 4 |
| GFRA4 | DEFB128 | 0.755643 | 3 | 0 | 3 |
| GFRA4 | C9orf153 | 0.754536 | 3 | 0 | 3 |
| GFRA4 | AMHR2 | 0.754343 | 7 | 0 | 7 |
| GFRA4 | KRTAP10-12 | 0.748356 | 3 | 0 | 3 |
| GFRA4 | C6 | 0.744498 | 4 | 0 | 4 |
| GFRA4 | OR2T27 | 0.742876 | 3 | 0 | 3 |
| GFRA4 | YY2 | 0.737663 | 3 | 0 | 3 |
| GFRA4 | KRTAP4-8 | 0.735812 | 5 | 0 | 5 |
| GFRA4 | ABCA4 | 0.733116 | 5 | 0 | 5 |
For details and further investigation, click here
