ZIM3

 

Full name: zinc finger imprinted 3 Alias Symbol: ZNF657
Type: protein-coding gene Cytoband: 19q13.43
Entrez ID: 114026 HGNC ID: HGNC:16366 Ensembl Gene: ENSG00000141946 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of ZIM3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZIM3 114026 1553022_at 0.1533 0.4448
GSE26886 ZIM3 114026 1553022_at 0.0093 0.9263
GSE45670 ZIM3 114026 1553022_at -0.0051 0.9578
GSE53622 ZIM3 114026 70890 -0.1573 0.0160
GSE53624 ZIM3 114026 70890 -0.0121 0.9128
GSE63941 ZIM3 114026 1553022_at -0.1594 0.2255
GSE77861 ZIM3 114026 1553022_at -0.0879 0.2564
TCGA ZIM3 114026 RNAseq 2.1347 0.3442

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by ZIM3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ZIM3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZIM3 114026 2 4 24
GSE20123 ZIM3 114026 2 3 25
GSE43470 ZIM3 114026 2 9 32
GSE46452 ZIM3 114026 45 1 13
GSE47630 ZIM3 114026 8 6 26
GSE54993 ZIM3 114026 18 4 48
GSE54994 ZIM3 114026 5 12 36
GSE60625 ZIM3 114026 9 0 2
GSE74703 ZIM3 114026 2 6 28
GSE74704 ZIM3 114026 2 1 17
TCGA ZIM3 114026 20 15 61

Total number of gains: 115; Total number of losses: 61; Total Number of normals: 312.  

 

Somatic mutations of ZIM3:

 

Generating mutation plots.

 

Highly correlated genes for ZIM3:

 

Showing all 12 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZIM3ZAR10.687838303
ZIM3HIVEP30.639942303
ZIM3OR5W20.590629303
ZIM3OR3A20.583966303
ZIM3LRRC450.583898403
ZIM3UROC10.580194303
ZIM3CCDC1680.578152303
ZIM3ARPC40.560596403
ZIM3FOXP40.546731403
ZIM3ASCL30.539832403
ZIM3MYH40.511715403
ZIM3DYDC10.501779403

For details and further investigation, click here