| Full name: actin related protein 2/3 complex subunit 4 | Alias Symbol: p20-Arc|ARC20 | ||
| Type: protein-coding gene | Cytoband: 3p25.3 | ||
| Entrez ID: 10093 | HGNC ID: HGNC:707 | Ensembl Gene: ENSG00000241553 | OMIM ID: 604226 |
Screen Evidence:
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ARPC4 involved pathways:
Expression of ARPC4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARPC4 | 10093 | 217817_at | 0.1851 | 0.4865 | |
| GSE20347 | ARPC4 | 10093 | 217817_at | -0.4452 | 0.0000 | |
| GSE23400 | ARPC4 | 10093 | 217817_at | -0.1154 | 0.0167 | |
| GSE26886 | ARPC4 | 10093 | 217817_at | -0.5696 | 0.0056 | |
| GSE29001 | ARPC4 | 10093 | 217817_at | -0.6296 | 0.0353 | |
| GSE38129 | ARPC4 | 10093 | 217817_at | -0.3212 | 0.0003 | |
| GSE45670 | ARPC4 | 10093 | 217817_at | 0.0110 | 0.9314 | |
| GSE63941 | ARPC4 | 10093 | 217817_at | -0.3513 | 0.2157 | |
| GSE77861 | ARPC4 | 10093 | 217817_at | -0.2117 | 0.1956 | |
| GSE97050 | ARPC4 | 10093 | A_24_P20383 | -0.1821 | 0.6886 | |
| SRP007169 | ARPC4 | 10093 | RNAseq | -1.3986 | 0.0009 | |
| SRP008496 | ARPC4 | 10093 | RNAseq | -1.5263 | 0.0000 | |
| SRP064894 | ARPC4 | 10093 | RNAseq | 0.0213 | 0.9397 | |
| SRP133303 | ARPC4 | 10093 | RNAseq | -0.2097 | 0.1274 | |
| SRP159526 | ARPC4 | 10093 | RNAseq | -0.6489 | 0.0013 | |
| SRP193095 | ARPC4 | 10093 | RNAseq | -0.6735 | 0.0000 | |
| SRP219564 | ARPC4 | 10093 | RNAseq | -0.2805 | 0.4355 | |
| TCGA | ARPC4 | 10093 | RNAseq | 0.0030 | 0.9494 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ARPC4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ARPC4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARPC4 | 10093 | 1 | 18 | 11 | |
| GSE20123 | ARPC4 | 10093 | 1 | 18 | 11 | |
| GSE43470 | ARPC4 | 10093 | 1 | 20 | 22 | |
| GSE46452 | ARPC4 | 10093 | 2 | 17 | 40 | |
| GSE47630 | ARPC4 | 10093 | 3 | 22 | 15 | |
| GSE54993 | ARPC4 | 10093 | 6 | 1 | 63 | |
| GSE54994 | ARPC4 | 10093 | 3 | 31 | 19 | |
| GSE60625 | ARPC4 | 10093 | 5 | 0 | 6 | |
| GSE74703 | ARPC4 | 10093 | 1 | 16 | 19 | |
| GSE74704 | ARPC4 | 10093 | 1 | 11 | 8 | |
| TCGA | ARPC4 | 10093 | 5 | 65 | 26 |
Total number of gains: 29; Total number of losses: 219; Total Number of normals: 240.
Somatic mutations of ARPC4:
Generating mutation plots.
Highly correlated genes for ARPC4:
Showing top 20/454 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARPC4 | MCOLN1 | 0.815691 | 3 | 0 | 3 |
| ARPC4 | RNFT2 | 0.752656 | 3 | 0 | 3 |
| ARPC4 | AKT1S1 | 0.739203 | 5 | 0 | 4 |
| ARPC4 | SPI1 | 0.731664 | 3 | 0 | 3 |
| ARPC4 | ZNF578 | 0.728069 | 3 | 0 | 3 |
| ARPC4 | CMTM6 | 0.724465 | 3 | 0 | 3 |
| ARPC4 | MUL1 | 0.723467 | 4 | 0 | 4 |
| ARPC4 | YIF1B | 0.716983 | 3 | 0 | 3 |
| ARPC4 | PNKP | 0.716706 | 3 | 0 | 3 |
| ARPC4 | SEC61B | 0.712168 | 3 | 0 | 3 |
| ARPC4 | CCDC7 | 0.711942 | 3 | 0 | 3 |
| ARPC4 | KEAP1 | 0.706638 | 3 | 0 | 3 |
| ARPC4 | GRAPL | 0.705881 | 3 | 0 | 3 |
| ARPC4 | ARFRP1 | 0.705779 | 4 | 0 | 4 |
| ARPC4 | PHKB | 0.69714 | 3 | 0 | 3 |
| ARPC4 | CCDC167 | 0.696037 | 4 | 0 | 4 |
| ARPC4 | GCDH | 0.695139 | 3 | 0 | 3 |
| ARPC4 | WDR82 | 0.69072 | 5 | 0 | 4 |
| ARPC4 | MFSD3 | 0.690305 | 3 | 0 | 3 |
| ARPC4 | TMEM129 | 0.690257 | 4 | 0 | 3 |
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