| Full name: leucine rich repeat containing 45 | Alias Symbol: MGC20806 | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 201255 | HGNC ID: HGNC:28302 | Ensembl Gene: ENSG00000169683 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC45:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC45 | 201255 | 226253_at | 0.6055 | 0.1969 | |
| GSE26886 | LRRC45 | 201255 | 226253_at | 0.3212 | 0.1063 | |
| GSE45670 | LRRC45 | 201255 | 226253_at | 0.2101 | 0.0464 | |
| GSE53622 | LRRC45 | 201255 | 38980 | 0.2953 | 0.0000 | |
| GSE53624 | LRRC45 | 201255 | 62045 | 0.5986 | 0.0000 | |
| GSE63941 | LRRC45 | 201255 | 226253_at | -0.2685 | 0.3279 | |
| GSE77861 | LRRC45 | 201255 | 226253_at | -0.0739 | 0.5943 | |
| GSE97050 | LRRC45 | 201255 | A_33_P3245947 | -0.0495 | 0.8728 | |
| SRP007169 | LRRC45 | 201255 | RNAseq | 0.7155 | 0.2501 | |
| SRP064894 | LRRC45 | 201255 | RNAseq | 1.2731 | 0.0000 | |
| SRP133303 | LRRC45 | 201255 | RNAseq | 0.4590 | 0.0269 | |
| SRP159526 | LRRC45 | 201255 | RNAseq | 0.7148 | 0.0275 | |
| SRP193095 | LRRC45 | 201255 | RNAseq | 0.2970 | 0.0090 | |
| SRP219564 | LRRC45 | 201255 | RNAseq | 0.9649 | 0.0410 | |
| TCGA | LRRC45 | 201255 | RNAseq | 0.0635 | 0.2964 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by LRRC45 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC45:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC45 | 201255 | 4 | 4 | 22 | |
| GSE20123 | LRRC45 | 201255 | 4 | 4 | 22 | |
| GSE43470 | LRRC45 | 201255 | 3 | 5 | 35 | |
| GSE46452 | LRRC45 | 201255 | 34 | 0 | 25 | |
| GSE47630 | LRRC45 | 201255 | 9 | 2 | 29 | |
| GSE54993 | LRRC45 | 201255 | 2 | 5 | 63 | |
| GSE54994 | LRRC45 | 201255 | 10 | 6 | 37 | |
| GSE60625 | LRRC45 | 201255 | 6 | 0 | 5 | |
| GSE74703 | LRRC45 | 201255 | 3 | 3 | 30 | |
| GSE74704 | LRRC45 | 201255 | 4 | 3 | 13 | |
| TCGA | LRRC45 | 201255 | 24 | 13 | 59 |
Total number of gains: 103; Total number of losses: 45; Total Number of normals: 340.
Somatic mutations of LRRC45:
Generating mutation plots.
Highly correlated genes for LRRC45:
Showing top 20/219 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC45 | AANAT | 0.777909 | 3 | 0 | 3 |
| LRRC45 | ABHD11 | 0.725862 | 3 | 0 | 3 |
| LRRC45 | TSPAN32 | 0.723838 | 3 | 0 | 3 |
| LRRC45 | UMODL1 | 0.71986 | 3 | 0 | 3 |
| LRRC45 | CHEK2 | 0.710196 | 4 | 0 | 4 |
| LRRC45 | RNF157-AS1 | 0.707406 | 3 | 0 | 3 |
| LRRC45 | NAT8B | 0.706267 | 3 | 0 | 3 |
| LRRC45 | MAGEB2 | 0.70622 | 3 | 0 | 3 |
| LRRC45 | S100Z | 0.70126 | 3 | 0 | 3 |
| LRRC45 | CLDN9 | 0.697285 | 3 | 0 | 3 |
| LRRC45 | ARMC7 | 0.688266 | 5 | 0 | 5 |
| LRRC45 | ZNF524 | 0.687196 | 3 | 0 | 3 |
| LRRC45 | DOK7 | 0.680535 | 3 | 0 | 3 |
| LRRC45 | IRAK1 | 0.677629 | 4 | 0 | 3 |
| LRRC45 | LENG1 | 0.671596 | 3 | 0 | 3 |
| LRRC45 | SUV39H1 | 0.670917 | 4 | 0 | 4 |
| LRRC45 | MFSD11 | 0.670568 | 3 | 0 | 3 |
| LRRC45 | WRAP53 | 0.665996 | 4 | 0 | 4 |
| LRRC45 | ASF1B | 0.659414 | 6 | 0 | 5 |
| LRRC45 | MEX3D | 0.658298 | 4 | 0 | 3 |
For details and further investigation, click here
