| Full name: zinc finger protein 677 | Alias Symbol: MGC48625 | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 342926 | HGNC ID: HGNC:28730 | Ensembl Gene: ENSG00000197928 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF677:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF677 | 342926 | 228974_at | -1.2417 | 0.3377 | |
| GSE26886 | ZNF677 | 342926 | 228974_at | -2.1337 | 0.0000 | |
| GSE45670 | ZNF677 | 342926 | 228974_at | -1.8648 | 0.0005 | |
| GSE53622 | ZNF677 | 342926 | 138885 | -0.8656 | 0.0000 | |
| GSE53624 | ZNF677 | 342926 | 138885 | -1.0538 | 0.0000 | |
| GSE63941 | ZNF677 | 342926 | 228974_at | -4.3909 | 0.0000 | |
| GSE77861 | ZNF677 | 342926 | 1560562_a_at | -0.2482 | 0.0797 | |
| GSE97050 | ZNF677 | 342926 | A_33_P3231705 | -0.2770 | 0.5864 | |
| SRP007169 | ZNF677 | 342926 | RNAseq | -0.3459 | 0.6450 | |
| SRP064894 | ZNF677 | 342926 | RNAseq | -1.0875 | 0.0006 | |
| SRP133303 | ZNF677 | 342926 | RNAseq | -0.6286 | 0.0022 | |
| SRP159526 | ZNF677 | 342926 | RNAseq | -1.7548 | 0.0000 | |
| SRP193095 | ZNF677 | 342926 | RNAseq | -0.5621 | 0.0003 | |
| SRP219564 | ZNF677 | 342926 | RNAseq | -0.8117 | 0.2533 | |
| TCGA | ZNF677 | 342926 | RNAseq | -1.4843 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by ZNF677 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF677:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF677 | 342926 | 3 | 4 | 23 | |
| GSE20123 | ZNF677 | 342926 | 3 | 3 | 24 | |
| GSE43470 | ZNF677 | 342926 | 2 | 11 | 30 | |
| GSE46452 | ZNF677 | 342926 | 45 | 1 | 13 | |
| GSE47630 | ZNF677 | 342926 | 8 | 6 | 26 | |
| GSE54993 | ZNF677 | 342926 | 17 | 4 | 49 | |
| GSE54994 | ZNF677 | 342926 | 4 | 14 | 35 | |
| GSE60625 | ZNF677 | 342926 | 9 | 0 | 2 | |
| GSE74703 | ZNF677 | 342926 | 2 | 7 | 27 | |
| GSE74704 | ZNF677 | 342926 | 3 | 1 | 16 | |
| TCGA | ZNF677 | 342926 | 18 | 17 | 61 |
Total number of gains: 114; Total number of losses: 68; Total Number of normals: 306.
Somatic mutations of ZNF677:
Generating mutation plots.
Highly correlated genes for ZNF677:
Showing top 20/801 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF677 | ZNF471 | 0.793651 | 6 | 0 | 6 |
| ZNF677 | GALNT11 | 0.742427 | 3 | 0 | 3 |
| ZNF677 | PDZRN3 | 0.730232 | 5 | 0 | 5 |
| ZNF677 | ZNF626 | 0.728074 | 5 | 0 | 5 |
| ZNF677 | NICN1 | 0.725 | 4 | 0 | 4 |
| ZNF677 | ZNF667-AS1 | 0.716173 | 7 | 0 | 6 |
| ZNF677 | ZNF568 | 0.715818 | 3 | 0 | 3 |
| ZNF677 | ZNF667 | 0.714441 | 5 | 0 | 4 |
| ZNF677 | RERE | 0.711701 | 4 | 0 | 4 |
| ZNF677 | ACTG2 | 0.707676 | 5 | 0 | 4 |
| ZNF677 | ZNF583 | 0.704913 | 4 | 0 | 3 |
| ZNF677 | SLC27A6 | 0.70262 | 8 | 0 | 8 |
| ZNF677 | ZFP28 | 0.695641 | 7 | 0 | 7 |
| ZNF677 | CNTN4 | 0.688932 | 4 | 0 | 4 |
| ZNF677 | ZNF415 | 0.688727 | 8 | 0 | 6 |
| ZNF677 | ZNF829 | 0.687483 | 6 | 0 | 5 |
| ZNF677 | MAGI2-AS3 | 0.686591 | 5 | 0 | 5 |
| ZNF677 | LINC01279 | 0.68631 | 3 | 0 | 3 |
| ZNF677 | ZNF844 | 0.6832 | 7 | 0 | 6 |
| ZNF677 | ZNF132 | 0.681121 | 3 | 0 | 3 |
For details and further investigation, click here
