| Full name: nicolin 1 | Alias Symbol: MGC12936 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 84276 | HGNC ID: HGNC:18317 | Ensembl Gene: ENSG00000145029 | OMIM ID: 611516 |
| Drug and gene relationship at DGIdb | |||
Expression of NICN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NICN1 | 84276 | 223442_at | -0.2080 | 0.5230 | |
| GSE26886 | NICN1 | 84276 | 223442_at | -0.8894 | 0.0000 | |
| GSE45670 | NICN1 | 84276 | 223442_at | -0.1258 | 0.3836 | |
| GSE63941 | NICN1 | 84276 | 223442_at | -1.1294 | 0.0034 | |
| GSE77861 | NICN1 | 84276 | 223442_at | -0.2334 | 0.0346 | |
| GSE97050 | NICN1 | 84276 | A_23_P110005 | -0.1147 | 0.6209 | |
| SRP007169 | NICN1 | 84276 | RNAseq | -1.3127 | 0.0021 | |
| SRP008496 | NICN1 | 84276 | RNAseq | -0.7957 | 0.0179 | |
| SRP064894 | NICN1 | 84276 | RNAseq | -0.3521 | 0.1234 | |
| SRP133303 | NICN1 | 84276 | RNAseq | -0.5870 | 0.0003 | |
| SRP159526 | NICN1 | 84276 | RNAseq | -0.5290 | 0.0171 | |
| SRP193095 | NICN1 | 84276 | RNAseq | -0.3531 | 0.0011 | |
| SRP219564 | NICN1 | 84276 | RNAseq | -0.4847 | 0.3487 | |
| TCGA | NICN1 | 84276 | RNAseq | -0.5470 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by NICN1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of NICN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NICN1 | 84276 | 0 | 18 | 12 | |
| GSE20123 | NICN1 | 84276 | 0 | 19 | 11 | |
| GSE43470 | NICN1 | 84276 | 0 | 18 | 25 | |
| GSE46452 | NICN1 | 84276 | 2 | 16 | 41 | |
| GSE47630 | NICN1 | 84276 | 1 | 24 | 15 | |
| GSE54993 | NICN1 | 84276 | 6 | 2 | 62 | |
| GSE54994 | NICN1 | 84276 | 0 | 36 | 17 | |
| GSE60625 | NICN1 | 84276 | 5 | 0 | 6 | |
| GSE74703 | NICN1 | 84276 | 0 | 14 | 22 | |
| GSE74704 | NICN1 | 84276 | 0 | 12 | 8 | |
| TCGA | NICN1 | 84276 | 0 | 78 | 18 |
Total number of gains: 14; Total number of losses: 237; Total Number of normals: 237.
Somatic mutations of NICN1:
Generating mutation plots.
Highly correlated genes for NICN1:
Showing top 20/158 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NICN1 | ENTPD5 | 0.806183 | 3 | 0 | 3 |
| NICN1 | DIO2 | 0.78845 | 3 | 0 | 3 |
| NICN1 | GRIPAP1 | 0.78169 | 3 | 0 | 3 |
| NICN1 | UBN2 | 0.780967 | 3 | 0 | 3 |
| NICN1 | ABCD3 | 0.763058 | 4 | 0 | 3 |
| NICN1 | PDZD2 | 0.760299 | 4 | 0 | 3 |
| NICN1 | AP4B1 | 0.759124 | 3 | 0 | 3 |
| NICN1 | RASSF6 | 0.753235 | 3 | 0 | 3 |
| NICN1 | BCL2L15 | 0.747145 | 3 | 0 | 3 |
| NICN1 | ZNF575 | 0.741156 | 3 | 0 | 3 |
| NICN1 | MFSD1 | 0.730747 | 4 | 0 | 3 |
| NICN1 | PRRG1 | 0.726684 | 4 | 0 | 3 |
| NICN1 | RAET1E | 0.726496 | 3 | 0 | 3 |
| NICN1 | ZNF677 | 0.725 | 4 | 0 | 4 |
| NICN1 | ALDH1L1 | 0.724899 | 3 | 0 | 3 |
| NICN1 | LIMD1 | 0.722975 | 3 | 0 | 3 |
| NICN1 | KCNK12 | 0.719489 | 3 | 0 | 3 |
| NICN1 | CYP4B1 | 0.717278 | 3 | 0 | 3 |
| NICN1 | TDRD7 | 0.714211 | 3 | 0 | 3 |
| NICN1 | TNR | 0.71412 | 3 | 0 | 3 |
For details and further investigation, click here
