| Full name: ZFP28 zinc finger protein | Alias Symbol: KIAA1431|mkr5 | ||
| Type: protein-coding gene | Cytoband: 19q13.43 | ||
| Entrez ID: 140612 | HGNC ID: HGNC:17801 | Ensembl Gene: ENSG00000196867 | OMIM ID: 616798 |
| Drug and gene relationship at DGIdb | |||
Expression of ZFP28:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZFP28 | 140612 | 234937_x_at | -0.4573 | 0.5980 | |
| GSE26886 | ZFP28 | 140612 | 234937_x_at | -0.5153 | 0.0002 | |
| GSE45670 | ZFP28 | 140612 | 231943_at | -0.5421 | 0.0047 | |
| GSE53622 | ZFP28 | 140612 | 28851 | -1.4820 | 0.0000 | |
| GSE53624 | ZFP28 | 140612 | 28851 | -1.6007 | 0.0000 | |
| GSE63941 | ZFP28 | 140612 | 234937_x_at | -1.0699 | 0.0154 | |
| GSE77861 | ZFP28 | 140612 | 234937_x_at | -0.1895 | 0.1761 | |
| SRP064894 | ZFP28 | 140612 | RNAseq | -0.5519 | 0.1079 | |
| SRP133303 | ZFP28 | 140612 | RNAseq | -0.6670 | 0.0040 | |
| SRP159526 | ZFP28 | 140612 | RNAseq | -1.3531 | 0.0003 | |
| SRP193095 | ZFP28 | 140612 | RNAseq | -0.7310 | 0.0007 | |
| SRP219564 | ZFP28 | 140612 | RNAseq | -0.9417 | 0.1035 | |
| TCGA | ZFP28 | 140612 | RNAseq | -0.8277 | 0.0034 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by ZFP28 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZFP28:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZFP28 | 140612 | 2 | 4 | 24 | |
| GSE20123 | ZFP28 | 140612 | 2 | 3 | 25 | |
| GSE43470 | ZFP28 | 140612 | 3 | 9 | 31 | |
| GSE46452 | ZFP28 | 140612 | 45 | 1 | 13 | |
| GSE47630 | ZFP28 | 140612 | 8 | 6 | 26 | |
| GSE54993 | ZFP28 | 140612 | 18 | 4 | 48 | |
| GSE54994 | ZFP28 | 140612 | 5 | 12 | 36 | |
| GSE60625 | ZFP28 | 140612 | 9 | 0 | 2 | |
| GSE74703 | ZFP28 | 140612 | 3 | 6 | 27 | |
| GSE74704 | ZFP28 | 140612 | 2 | 1 | 17 | |
| TCGA | ZFP28 | 140612 | 19 | 16 | 61 |
Total number of gains: 116; Total number of losses: 62; Total Number of normals: 310.
Somatic mutations of ZFP28:
Generating mutation plots.
Highly correlated genes for ZFP28:
Showing top 20/469 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZFP28 | ZNF471 | 0.753199 | 6 | 0 | 6 |
| ZFP28 | ZNF829 | 0.724537 | 6 | 0 | 6 |
| ZFP28 | KCNB1 | 0.699249 | 3 | 0 | 3 |
| ZFP28 | ZNF677 | 0.695641 | 7 | 0 | 7 |
| ZFP28 | PCSK2 | 0.684489 | 3 | 0 | 3 |
| ZFP28 | ZNF880 | 0.677718 | 4 | 0 | 4 |
| ZFP28 | C1QTNF7 | 0.674091 | 4 | 0 | 4 |
| ZFP28 | ZNF667-AS1 | 0.672615 | 7 | 0 | 7 |
| ZFP28 | SORBS1 | 0.66789 | 3 | 0 | 3 |
| ZFP28 | ZSCAN18 | 0.662301 | 7 | 0 | 6 |
| ZFP28 | PGM5 | 0.658742 | 4 | 0 | 4 |
| ZFP28 | NEGR1 | 0.657293 | 5 | 0 | 5 |
| ZFP28 | A2ML1 | 0.657133 | 3 | 0 | 3 |
| ZFP28 | SYPL2 | 0.656754 | 3 | 0 | 3 |
| ZFP28 | SORCS1 | 0.656199 | 3 | 0 | 3 |
| ZFP28 | ZNF415 | 0.650953 | 6 | 0 | 5 |
| ZFP28 | ID4 | 0.650904 | 4 | 0 | 4 |
| ZFP28 | CDH19 | 0.650004 | 4 | 0 | 4 |
| ZFP28 | ATOH8 | 0.64747 | 3 | 0 | 3 |
| ZFP28 | MBNL1-AS1 | 0.643495 | 4 | 0 | 4 |
For details and further investigation, click here
