| Full name: contactin 4 | Alias Symbol: BIG-2 | ||
| Type: protein-coding gene | Cytoband: 3p26.3-p26.2 | ||
| Entrez ID: 152330 | HGNC ID: HGNC:2174 | Ensembl Gene: ENSG00000144619 | OMIM ID: 607280 |
| Drug and gene relationship at DGIdb | |||
Expression of CNTN4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CNTN4 | 152330 | 229084_at | -1.5096 | 0.0423 | |
| GSE26886 | CNTN4 | 152330 | 229084_at | -0.1561 | 0.5523 | |
| GSE45670 | CNTN4 | 152330 | 229084_at | -2.3612 | 0.0000 | |
| GSE53622 | CNTN4 | 152330 | 14919 | -0.4902 | 0.0000 | |
| GSE53624 | CNTN4 | 152330 | 14919 | -0.9251 | 0.0000 | |
| GSE63941 | CNTN4 | 152330 | 229084_at | -6.2104 | 0.0000 | |
| GSE77861 | CNTN4 | 152330 | 237177_at | -0.1209 | 0.1539 | |
| GSE97050 | CNTN4 | 152330 | A_23_P144020 | -0.0217 | 0.9710 | |
| SRP007169 | CNTN4 | 152330 | RNAseq | 1.0048 | 0.1385 | |
| SRP064894 | CNTN4 | 152330 | RNAseq | -0.4713 | 0.2759 | |
| SRP133303 | CNTN4 | 152330 | RNAseq | -0.6384 | 0.0696 | |
| SRP159526 | CNTN4 | 152330 | RNAseq | -0.9556 | 0.0176 | |
| SRP193095 | CNTN4 | 152330 | RNAseq | 0.0939 | 0.7947 | |
| SRP219564 | CNTN4 | 152330 | RNAseq | -0.1621 | 0.7979 | |
| TCGA | CNTN4 | 152330 | RNAseq | -1.2397 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by CNTN4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CNTN4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CNTN4 | 152330 | 1 | 19 | 10 | |
| GSE20123 | CNTN4 | 152330 | 1 | 19 | 10 | |
| GSE43470 | CNTN4 | 152330 | 0 | 21 | 22 | |
| GSE46452 | CNTN4 | 152330 | 2 | 18 | 39 | |
| GSE47630 | CNTN4 | 152330 | 2 | 23 | 15 | |
| GSE54993 | CNTN4 | 152330 | 6 | 1 | 63 | |
| GSE54994 | CNTN4 | 152330 | 2 | 31 | 20 | |
| GSE60625 | CNTN4 | 152330 | 2 | 3 | 6 | |
| GSE74703 | CNTN4 | 152330 | 0 | 18 | 18 | |
| GSE74704 | CNTN4 | 152330 | 1 | 12 | 7 | |
| TCGA | CNTN4 | 152330 | 2 | 68 | 26 |
Total number of gains: 19; Total number of losses: 233; Total Number of normals: 236.
Somatic mutations of CNTN4:
Generating mutation plots.
Highly correlated genes for CNTN4:
Showing top 20/255 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CNTN4 | LAMA2 | 0.895556 | 3 | 0 | 3 |
| CNTN4 | LINC01082 | 0.873863 | 3 | 0 | 3 |
| CNTN4 | RAI2 | 0.863545 | 3 | 0 | 3 |
| CNTN4 | PGM5-AS1 | 0.847055 | 3 | 0 | 3 |
| CNTN4 | ABCA9 | 0.838252 | 3 | 0 | 3 |
| CNTN4 | SMIM10 | 0.83052 | 3 | 0 | 3 |
| CNTN4 | FENDRR | 0.816524 | 3 | 0 | 3 |
| CNTN4 | MAGEL2 | 0.815998 | 3 | 0 | 3 |
| CNTN4 | MICU3 | 0.798234 | 3 | 0 | 3 |
| CNTN4 | ZNF667-AS1 | 0.77287 | 3 | 0 | 3 |
| CNTN4 | EPB41L4A-AS1 | 0.770379 | 3 | 0 | 3 |
| CNTN4 | MAGI2-AS3 | 0.765977 | 4 | 0 | 4 |
| CNTN4 | FAT4 | 0.762606 | 4 | 0 | 3 |
| CNTN4 | LINC01279 | 0.759727 | 4 | 0 | 4 |
| CNTN4 | SNED1 | 0.756113 | 4 | 0 | 4 |
| CNTN4 | TMEM100 | 0.755603 | 5 | 0 | 4 |
| CNTN4 | RPL3 | 0.751414 | 3 | 0 | 3 |
| CNTN4 | MGARP | 0.750171 | 3 | 0 | 3 |
| CNTN4 | SCN3A | 0.749409 | 3 | 0 | 3 |
| CNTN4 | GSTM5 | 0.743867 | 6 | 0 | 5 |
For details and further investigation, click here
