| Full name: ataxin 7 like 1 | Alias Symbol: KIAA1218|MGC33190 | ||
| Type: protein-coding gene | Cytoband: 7q22.3 | ||
| Entrez ID: 222255 | HGNC ID: HGNC:22210 | Ensembl Gene: ENSG00000146776 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ATXN7L1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATXN7L1 | 222255 | 227732_at | -0.0832 | 0.9149 | |
| GSE20347 | ATXN7L1 | 222255 | 214343_s_at | 0.0089 | 0.9412 | |
| GSE23400 | ATXN7L1 | 222255 | 214342_at | -0.0317 | 0.3153 | |
| GSE26886 | ATXN7L1 | 222255 | 227732_at | 0.6733 | 0.0024 | |
| GSE29001 | ATXN7L1 | 222255 | 214342_at | -0.1528 | 0.2245 | |
| GSE38129 | ATXN7L1 | 222255 | 214343_s_at | 0.1441 | 0.2956 | |
| GSE45670 | ATXN7L1 | 222255 | 227732_at | -0.0646 | 0.7724 | |
| GSE53622 | ATXN7L1 | 222255 | 121089 | -0.1876 | 0.0541 | |
| GSE53624 | ATXN7L1 | 222255 | 121089 | -0.1324 | 0.0253 | |
| GSE63941 | ATXN7L1 | 222255 | 227732_at | -0.5847 | 0.1378 | |
| GSE77861 | ATXN7L1 | 222255 | 227732_at | 0.1109 | 0.6853 | |
| GSE97050 | ATXN7L1 | 222255 | A_23_P356109 | 0.1978 | 0.5016 | |
| SRP007169 | ATXN7L1 | 222255 | RNAseq | 0.3399 | 0.5275 | |
| SRP008496 | ATXN7L1 | 222255 | RNAseq | 0.3718 | 0.3734 | |
| SRP064894 | ATXN7L1 | 222255 | RNAseq | -0.0381 | 0.7592 | |
| SRP133303 | ATXN7L1 | 222255 | RNAseq | -0.1695 | 0.2223 | |
| SRP159526 | ATXN7L1 | 222255 | RNAseq | -0.5758 | 0.0448 | |
| SRP193095 | ATXN7L1 | 222255 | RNAseq | 0.1577 | 0.3748 | |
| SRP219564 | ATXN7L1 | 222255 | RNAseq | 0.1190 | 0.7145 | |
| TCGA | ATXN7L1 | 222255 | RNAseq | -0.0916 | 0.1923 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ATXN7L1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATXN7L1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATXN7L1 | 222255 | 13 | 0 | 17 | |
| GSE20123 | ATXN7L1 | 222255 | 13 | 0 | 17 | |
| GSE43470 | ATXN7L1 | 222255 | 7 | 1 | 35 | |
| GSE46452 | ATXN7L1 | 222255 | 10 | 1 | 48 | |
| GSE47630 | ATXN7L1 | 222255 | 8 | 3 | 29 | |
| GSE54993 | ATXN7L1 | 222255 | 2 | 9 | 59 | |
| GSE54994 | ATXN7L1 | 222255 | 15 | 3 | 35 | |
| GSE60625 | ATXN7L1 | 222255 | 0 | 0 | 11 | |
| GSE74703 | ATXN7L1 | 222255 | 7 | 1 | 28 | |
| GSE74704 | ATXN7L1 | 222255 | 8 | 0 | 12 | |
| TCGA | ATXN7L1 | 222255 | 54 | 7 | 35 |
Total number of gains: 137; Total number of losses: 25; Total Number of normals: 326.
Somatic mutations of ATXN7L1:
Generating mutation plots.
Highly correlated genes for ATXN7L1:
Showing all 11 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATXN7L1 | ZNF618 | 0.666083 | 3 | 0 | 3 |
| ATXN7L1 | GEMIN4 | 0.614469 | 3 | 0 | 3 |
| ATXN7L1 | CAPS | 0.60688 | 3 | 0 | 3 |
| ATXN7L1 | SYT14 | 0.569242 | 3 | 0 | 3 |
| ATXN7L1 | WDR81 | 0.566005 | 4 | 0 | 3 |
| ATXN7L1 | ZNF704 | 0.561233 | 3 | 0 | 3 |
| ATXN7L1 | VGLL1 | 0.551466 | 3 | 0 | 3 |
| ATXN7L1 | TRIM56 | 0.550323 | 4 | 0 | 3 |
| ATXN7L1 | FAM160B1 | 0.538399 | 4 | 0 | 3 |
| ATXN7L1 | ARID1B | 0.510291 | 4 | 0 | 3 |
| ATXN7L1 | TRIM8 | 0.505965 | 5 | 0 | 3 |
For details and further investigation, click here
