| Full name: AT-rich interaction domain 1B | Alias Symbol: KIAA1235|ELD/OSA1|p250R|BAF250b|DAN15|6A3-5 | ||
| Type: protein-coding gene | Cytoband: 6q25.3 | ||
| Entrez ID: 57492 | HGNC ID: HGNC:18040 | Ensembl Gene: ENSG00000049618 | OMIM ID: 614556 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ARID1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARID1B | 57492 | 225181_at | 0.1848 | 0.7963 | |
| GSE26886 | ARID1B | 57492 | 1566989_at | -0.0743 | 0.7977 | |
| GSE45670 | ARID1B | 57492 | 225181_at | -0.0916 | 0.5750 | |
| GSE53622 | ARID1B | 57492 | 37109 | -0.1470 | 0.0095 | |
| GSE53624 | ARID1B | 57492 | 37109 | -0.2264 | 0.0000 | |
| GSE63941 | ARID1B | 57492 | 225181_at | -1.9629 | 0.0003 | |
| GSE77861 | ARID1B | 57492 | 225181_at | -0.1779 | 0.5707 | |
| GSE97050 | ARID1B | 57492 | A_33_P3291877 | 0.1434 | 0.5009 | |
| SRP007169 | ARID1B | 57492 | RNAseq | -0.3470 | 0.3217 | |
| SRP008496 | ARID1B | 57492 | RNAseq | -0.1367 | 0.5543 | |
| SRP064894 | ARID1B | 57492 | RNAseq | -0.2102 | 0.2566 | |
| SRP133303 | ARID1B | 57492 | RNAseq | -0.1943 | 0.0073 | |
| SRP159526 | ARID1B | 57492 | RNAseq | -0.4136 | 0.0268 | |
| SRP193095 | ARID1B | 57492 | RNAseq | -0.3284 | 0.0014 | |
| SRP219564 | ARID1B | 57492 | RNAseq | -0.3044 | 0.3260 | |
| TCGA | ARID1B | 57492 | RNAseq | -0.0546 | 0.1892 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ARID1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARID1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARID1B | 57492 | 1 | 5 | 24 | |
| GSE20123 | ARID1B | 57492 | 1 | 4 | 25 | |
| GSE43470 | ARID1B | 57492 | 4 | 0 | 39 | |
| GSE46452 | ARID1B | 57492 | 3 | 10 | 46 | |
| GSE47630 | ARID1B | 57492 | 9 | 4 | 27 | |
| GSE54993 | ARID1B | 57492 | 3 | 2 | 65 | |
| GSE54994 | ARID1B | 57492 | 8 | 8 | 37 | |
| GSE60625 | ARID1B | 57492 | 0 | 1 | 10 | |
| GSE74703 | ARID1B | 57492 | 4 | 0 | 32 | |
| GSE74704 | ARID1B | 57492 | 0 | 2 | 18 | |
| TCGA | ARID1B | 57492 | 12 | 24 | 60 |
Total number of gains: 45; Total number of losses: 60; Total Number of normals: 383.
Somatic mutations of ARID1B:
Generating mutation plots.
Highly correlated genes for ARID1B:
Showing top 20/187 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARID1B | KLHL20 | 0.835426 | 3 | 0 | 3 |
| ARID1B | CCAR1 | 0.818511 | 3 | 0 | 3 |
| ARID1B | NIPAL3 | 0.817636 | 3 | 0 | 3 |
| ARID1B | MAN2B2 | 0.793922 | 3 | 0 | 3 |
| ARID1B | ABHD16A | 0.785919 | 3 | 0 | 3 |
| ARID1B | RBM26 | 0.78524 | 3 | 0 | 3 |
| ARID1B | SLC35B3 | 0.777428 | 3 | 0 | 3 |
| ARID1B | GOLGA3 | 0.775948 | 3 | 0 | 3 |
| ARID1B | RSAD1 | 0.765817 | 3 | 0 | 3 |
| ARID1B | STAT2 | 0.761983 | 3 | 0 | 3 |
| ARID1B | TRIM8 | 0.761915 | 4 | 0 | 3 |
| ARID1B | SDAD1 | 0.760225 | 3 | 0 | 3 |
| ARID1B | SLC25A38 | 0.759932 | 3 | 0 | 3 |
| ARID1B | ZNF805 | 0.748902 | 3 | 0 | 3 |
| ARID1B | TMEM129 | 0.74873 | 3 | 0 | 3 |
| ARID1B | KBTBD6 | 0.743241 | 3 | 0 | 3 |
| ARID1B | ZNF432 | 0.734126 | 4 | 0 | 3 |
| ARID1B | FBXL4 | 0.732812 | 3 | 0 | 3 |
| ARID1B | GPR107 | 0.72811 | 3 | 0 | 3 |
| ARID1B | ERGIC1 | 0.72634 | 4 | 0 | 4 |
For details and further investigation, click here
