| Full name: synaptotagmin 14 | Alias Symbol: sytXIV|FLJ34198 | ||
| Type: protein-coding gene | Cytoband: 1q32.2 | ||
| Entrez ID: 255928 | HGNC ID: HGNC:23143 | Ensembl Gene: ENSG00000143469 | OMIM ID: 610949 |
| Drug and gene relationship at DGIdb | |||
Expression of SYT14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYT14 | 255928 | 1553654_at | 0.2481 | 0.4051 | |
| GSE26886 | SYT14 | 255928 | 1553654_at | 0.1587 | 0.1538 | |
| GSE45670 | SYT14 | 255928 | 1553654_at | 0.2667 | 0.0976 | |
| GSE53622 | SYT14 | 255928 | 90424 | 1.8572 | 0.0000 | |
| GSE53624 | SYT14 | 255928 | 90424 | 1.3628 | 0.0000 | |
| GSE63941 | SYT14 | 255928 | 1553654_at | -1.4597 | 0.1741 | |
| GSE77861 | SYT14 | 255928 | 1553654_at | 0.0917 | 0.3559 | |
| SRP007169 | SYT14 | 255928 | RNAseq | 4.4056 | 0.0000 | |
| SRP064894 | SYT14 | 255928 | RNAseq | 1.2693 | 0.0001 | |
| SRP133303 | SYT14 | 255928 | RNAseq | 0.5989 | 0.0010 | |
| SRP159526 | SYT14 | 255928 | RNAseq | 2.7652 | 0.0010 | |
| SRP193095 | SYT14 | 255928 | RNAseq | 1.5783 | 0.0000 | |
| SRP219564 | SYT14 | 255928 | RNAseq | 1.3699 | 0.0214 | |
| TCGA | SYT14 | 255928 | RNAseq | 2.0227 | 0.0000 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by SYT14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYT14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYT14 | 255928 | 11 | 0 | 19 | |
| GSE20123 | SYT14 | 255928 | 10 | 0 | 20 | |
| GSE43470 | SYT14 | 255928 | 7 | 0 | 36 | |
| GSE46452 | SYT14 | 255928 | 3 | 1 | 55 | |
| GSE47630 | SYT14 | 255928 | 15 | 0 | 25 | |
| GSE54993 | SYT14 | 255928 | 0 | 6 | 64 | |
| GSE54994 | SYT14 | 255928 | 14 | 0 | 39 | |
| GSE60625 | SYT14 | 255928 | 0 | 0 | 11 | |
| GSE74703 | SYT14 | 255928 | 7 | 0 | 29 | |
| GSE74704 | SYT14 | 255928 | 4 | 0 | 16 | |
| TCGA | SYT14 | 255928 | 44 | 3 | 49 |
Total number of gains: 115; Total number of losses: 10; Total Number of normals: 363.
Somatic mutations of SYT14:
Generating mutation plots.
Highly correlated genes for SYT14:
Showing top 20/46 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYT14 | LIG1 | 0.679128 | 3 | 0 | 3 |
| SYT14 | MAPKAPK5-AS1 | 0.668063 | 3 | 0 | 3 |
| SYT14 | DST | 0.659014 | 3 | 0 | 3 |
| SYT14 | JPH1 | 0.645791 | 3 | 0 | 3 |
| SYT14 | RAVER1 | 0.626306 | 3 | 0 | 3 |
| SYT14 | NAT9 | 0.625393 | 3 | 0 | 3 |
| SYT14 | BRF2 | 0.619846 | 4 | 0 | 3 |
| SYT14 | SYCP2 | 0.608265 | 4 | 0 | 3 |
| SYT14 | MUCL1 | 0.605171 | 4 | 0 | 3 |
| SYT14 | C17orf100 | 0.601826 | 3 | 0 | 3 |
| SYT14 | BRIX1 | 0.598252 | 4 | 0 | 3 |
| SYT14 | GTPBP6 | 0.593655 | 3 | 0 | 3 |
| SYT14 | THUMPD2 | 0.593589 | 3 | 0 | 3 |
| SYT14 | FAM24B | 0.593196 | 3 | 0 | 3 |
| SYT14 | NUP155 | 0.588263 | 4 | 0 | 3 |
| SYT14 | XCL1 | 0.580876 | 3 | 0 | 3 |
| SYT14 | MRPS28 | 0.575519 | 3 | 0 | 3 |
| SYT14 | TCHH | 0.573193 | 3 | 0 | 3 |
| SYT14 | ATXN7L1 | 0.569242 | 3 | 0 | 3 |
| SYT14 | ZNF7 | 0.563647 | 4 | 0 | 3 |
For details and further investigation, click here
