TRIM56

 

Full name: tripartite motif containing 56 Alias Symbol: RNF109
Type: protein-coding gene Cytoband: 7q22.1
Entrez ID: 81844 HGNC ID: HGNC:19028 Ensembl Gene: ENSG00000169871 OMIM ID: 616996
Drug and gene relationship at DGIdb

 

Expression of TRIM56:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TRIM56 81844 231876_at 0.1548 0.7864
GSE26886 TRIM56 81844 231876_at -0.3304 0.2719
GSE45670 TRIM56 81844 231876_at 0.0071 0.9784
GSE53622 TRIM56 81844 98986 -0.0997 0.3436
GSE53624 TRIM56 81844 98986 -0.4056 0.0000
GSE63941 TRIM56 81844 231876_at -1.1735 0.0253
GSE77861 TRIM56 81844 231876_at -0.2575 0.2289
GSE97050 TRIM56 81844 A_23_P350107 -0.5177 0.1782
SRP007169 TRIM56 81844 RNAseq -0.1762 0.6806
SRP008496 TRIM56 81844 RNAseq -0.3887 0.0916
SRP064894 TRIM56 81844 RNAseq -0.4342 0.0381
SRP133303 TRIM56 81844 RNAseq -0.2047 0.0918
SRP159526 TRIM56 81844 RNAseq -0.4677 0.1234
SRP193095 TRIM56 81844 RNAseq 0.0941 0.5012
SRP219564 TRIM56 81844 RNAseq 0.1545 0.6787
TCGA TRIM56 81844 RNAseq -0.0587 0.3197

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by TRIM56 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of TRIM56:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TRIM56 81844 13 0 17
GSE20123 TRIM56 81844 13 0 17
GSE43470 TRIM56 81844 7 2 34
GSE46452 TRIM56 81844 11 1 47
GSE47630 TRIM56 81844 7 3 30
GSE54993 TRIM56 81844 1 10 59
GSE54994 TRIM56 81844 15 3 35
GSE60625 TRIM56 81844 0 0 11
GSE74703 TRIM56 81844 7 1 28
GSE74704 TRIM56 81844 9 0 11
TCGA TRIM56 81844 53 6 37

Total number of gains: 136; Total number of losses: 26; Total Number of normals: 326.  


 

Somatic mutations of TRIM56:

 

Generating mutation plots.

 

Highly correlated genes for TRIM56:

 

Showing top 20/131 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TRIM56LUC7L30.784718303
TRIM56TTC170.773781303
TRIM56ZNF5570.767409303
TRIM56CYTH20.745544303
TRIM56AKAP17A0.738695303
TRIM56GPR1070.72952303
TRIM56SLC35B30.718909303
TRIM56GAS60.718329303
TRIM56MED230.711125403
TRIM56ZDHHC140.70529303
TRIM56PCMTD10.705119303
TRIM56MOSPD20.704293303
TRIM56GTF2H50.703761303
TRIM56ZFP30.702397303
TRIM56WDTC10.700742404
TRIM56ANKHD10.696398404
TRIM56DYNLT10.692419303
TRIM56TMEM1810.690668303
TRIM56ENSA0.688236303
TRIM56GNL30.683719303

For details and further investigation, click here