| Full name: angiotensin I converting enzyme 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: Xp22.2 | ||
| Entrez ID: 59272 | HGNC ID: HGNC:13557 | Ensembl Gene: ENSG00000130234 | OMIM ID: 300335 |
| Drug and gene relationship at DGIdb | |||
Expression of ACE2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACE2 | 59272 | 222257_s_at | -0.6446 | 0.2173 | |
| GSE20347 | ACE2 | 59272 | 222257_s_at | -0.3241 | 0.0214 | |
| GSE23400 | ACE2 | 59272 | 222257_s_at | -0.3278 | 0.0000 | |
| GSE26886 | ACE2 | 59272 | 222257_s_at | -1.4022 | 0.0000 | |
| GSE29001 | ACE2 | 59272 | 222257_s_at | -0.4182 | 0.3483 | |
| GSE38129 | ACE2 | 59272 | 222257_s_at | -0.3058 | 0.1165 | |
| GSE45670 | ACE2 | 59272 | 222257_s_at | 0.1543 | 0.6648 | |
| GSE53622 | ACE2 | 59272 | 63716 | -1.2478 | 0.0001 | |
| GSE53624 | ACE2 | 59272 | 63716 | -1.4580 | 0.0000 | |
| GSE63941 | ACE2 | 59272 | 222257_s_at | 0.6578 | 0.3284 | |
| GSE77861 | ACE2 | 59272 | 222257_s_at | -0.6819 | 0.0007 | |
| SRP007169 | ACE2 | 59272 | RNAseq | -1.8969 | 0.0108 | |
| SRP008496 | ACE2 | 59272 | RNAseq | -2.3981 | 0.0000 | |
| SRP064894 | ACE2 | 59272 | RNAseq | -1.6022 | 0.0000 | |
| SRP133303 | ACE2 | 59272 | RNAseq | -0.0263 | 0.9511 | |
| SRP159526 | ACE2 | 59272 | RNAseq | -1.4431 | 0.0814 | |
| SRP193095 | ACE2 | 59272 | RNAseq | -1.2797 | 0.0003 | |
| SRP219564 | ACE2 | 59272 | RNAseq | 0.4979 | 0.5967 | |
| TCGA | ACE2 | 59272 | RNAseq | 0.0768 | 0.8061 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by ACE2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACE2:
No record found for this gene.
Somatic mutations of ACE2:
Generating mutation plots.
Highly correlated genes for ACE2:
Showing top 20/739 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACE2 | SPNS2 | 0.785866 | 3 | 0 | 3 |
| ACE2 | ANKRD22 | 0.764808 | 3 | 0 | 3 |
| ACE2 | ATP13A4 | 0.726234 | 5 | 0 | 5 |
| ACE2 | SH3PXD2A-AS1 | 0.717053 | 3 | 0 | 3 |
| ACE2 | ARHGAP27 | 0.707016 | 5 | 0 | 5 |
| ACE2 | SPAG17 | 0.705637 | 4 | 0 | 3 |
| ACE2 | MAB21L3 | 0.682897 | 6 | 0 | 6 |
| ACE2 | GCHFR | 0.680387 | 6 | 0 | 6 |
| ACE2 | PRSS27 | 0.67665 | 5 | 0 | 5 |
| ACE2 | S100A16 | 0.674442 | 5 | 0 | 5 |
| ACE2 | C15orf62 | 0.673378 | 5 | 0 | 4 |
| ACE2 | TRNP1 | 0.66907 | 5 | 0 | 3 |
| ACE2 | TPRG1 | 0.667869 | 5 | 0 | 4 |
| ACE2 | SFTA2 | 0.667346 | 4 | 0 | 3 |
| ACE2 | PITRM1-AS1 | 0.666694 | 3 | 0 | 3 |
| ACE2 | A2ML1 | 0.666044 | 5 | 0 | 4 |
| ACE2 | SPINK7 | 0.664891 | 5 | 0 | 4 |
| ACE2 | RAET1E | 0.662535 | 6 | 0 | 6 |
| ACE2 | FCHO2 | 0.661755 | 5 | 0 | 4 |
| ACE2 | CNFN | 0.660057 | 5 | 0 | 4 |
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