CCDC54

 

Full name: coiled-coil domain containing 54 Alias Symbol: NYD-SP17|FLJ25362|SP17
Type: protein-coding gene Cytoband: 3q13.12
Entrez ID: 84692 HGNC ID: HGNC:30703 Ensembl Gene: ENSG00000138483 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of CCDC54:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CCDC54 84692 244735_at 0.0109 0.9740
GSE26886 CCDC54 84692 244735_at 0.0823 0.3923
GSE45670 CCDC54 84692 244735_at 0.0529 0.5099
GSE53622 CCDC54 84692 47812 0.6039 0.0048
GSE53624 CCDC54 84692 47812 0.3463 0.0014
GSE63941 CCDC54 84692 244735_at -0.0182 0.9217
GSE77861 CCDC54 84692 244735_at -0.1563 0.1337
TCGA CCDC54 84692 RNAseq 1.2926 0.2199

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by CCDC54 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CCDC54:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CCDC54 84692 17 1 12
GSE20123 CCDC54 84692 16 1 13
GSE43470 CCDC54 84692 18 1 24
GSE46452 CCDC54 84692 12 6 41
GSE47630 CCDC54 84692 16 6 18
GSE54993 CCDC54 84692 2 5 63
GSE54994 CCDC54 84692 28 5 20
GSE60625 CCDC54 84692 0 6 5
GSE74703 CCDC54 84692 15 1 20
GSE74704 CCDC54 84692 13 1 6
TCGA CCDC54 84692 49 9 38

Total number of gains: 186; Total number of losses: 42; Total Number of normals: 260.  

 

Somatic mutations of CCDC54:

 

Generating mutation plots.

 

Highly correlated genes for CCDC54:

 

Showing all 10 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CCDC54RNF2120.652463303
CCDC54LINC009060.63158303
CCDC54ABCC120.603703303
CCDC54TAS2R80.572047403
CCDC54BPIFA30.569543303
CCDC54ZNF582-AS10.565022303
CCDC54DEFB1210.539296303
CCDC54IFNL10.521669403
CCDC54FSCN30.519834403
CCDC54MRGPRG-AS10.512019303

For details and further investigation, click here