| Full name: fascin actin-bundling protein 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7q32.1 | ||
| Entrez ID: 29999 | HGNC ID: HGNC:3961 | Ensembl Gene: ENSG00000106328 | OMIM ID: 615800 |
| Drug and gene relationship at DGIdb | |||
Expression of FSCN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FSCN3 | 29999 | 220379_at | -0.1285 | 0.5751 | |
| GSE20347 | FSCN3 | 29999 | 220379_at | 0.0353 | 0.7694 | |
| GSE23400 | FSCN3 | 29999 | 220379_at | -0.1833 | 0.0000 | |
| GSE26886 | FSCN3 | 29999 | 220379_at | -0.0050 | 0.9704 | |
| GSE29001 | FSCN3 | 29999 | 220379_at | -0.1826 | 0.3816 | |
| GSE38129 | FSCN3 | 29999 | 220379_at | -0.1040 | 0.3947 | |
| GSE45670 | FSCN3 | 29999 | 220379_at | 0.1466 | 0.1075 | |
| GSE53622 | FSCN3 | 29999 | 70353 | 0.0727 | 0.6439 | |
| GSE53624 | FSCN3 | 29999 | 70353 | 0.2600 | 0.0115 | |
| GSE63941 | FSCN3 | 29999 | 220379_at | -0.0696 | 0.6279 | |
| GSE77861 | FSCN3 | 29999 | 220379_at | -0.1023 | 0.4134 | |
| GSE97050 | FSCN3 | 29999 | A_23_P93898 | -0.0120 | 0.9613 | |
| TCGA | FSCN3 | 29999 | RNAseq | 0.3212 | 0.1607 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FSCN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FSCN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FSCN3 | 29999 | 7 | 1 | 22 | |
| GSE20123 | FSCN3 | 29999 | 7 | 2 | 21 | |
| GSE43470 | FSCN3 | 29999 | 2 | 3 | 38 | |
| GSE46452 | FSCN3 | 29999 | 7 | 2 | 50 | |
| GSE47630 | FSCN3 | 29999 | 7 | 4 | 29 | |
| GSE54993 | FSCN3 | 29999 | 3 | 5 | 62 | |
| GSE54994 | FSCN3 | 29999 | 9 | 7 | 37 | |
| GSE60625 | FSCN3 | 29999 | 0 | 0 | 11 | |
| GSE74703 | FSCN3 | 29999 | 2 | 3 | 31 | |
| GSE74704 | FSCN3 | 29999 | 3 | 2 | 15 | |
| TCGA | FSCN3 | 29999 | 27 | 22 | 47 |
Total number of gains: 74; Total number of losses: 51; Total Number of normals: 363.
Somatic mutations of FSCN3:
Generating mutation plots.
Highly correlated genes for FSCN3:
Showing top 20/1179 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FSCN3 | CHST13 | 0.748518 | 3 | 0 | 3 |
| FSCN3 | KIR3DL3 | 0.740719 | 6 | 0 | 6 |
| FSCN3 | STRC | 0.739742 | 3 | 0 | 3 |
| FSCN3 | PLA2G2C | 0.738898 | 3 | 0 | 3 |
| FSCN3 | IFNA4 | 0.734345 | 6 | 0 | 6 |
| FSCN3 | NTNG1 | 0.730753 | 4 | 0 | 4 |
| FSCN3 | SLC5A4 | 0.73048 | 6 | 0 | 5 |
| FSCN3 | MEGF11 | 0.729586 | 4 | 0 | 3 |
| FSCN3 | CCDC87 | 0.726361 | 5 | 0 | 5 |
| FSCN3 | PRODH2 | 0.723617 | 6 | 0 | 5 |
| FSCN3 | ANKRD33B | 0.722341 | 3 | 0 | 3 |
| FSCN3 | MFSD11 | 0.717964 | 3 | 0 | 3 |
| FSCN3 | CER1 | 0.716719 | 6 | 0 | 6 |
| FSCN3 | CYP11B1 | 0.715444 | 6 | 0 | 6 |
| FSCN3 | ABCC6 | 0.714727 | 3 | 0 | 3 |
| FSCN3 | SUN5 | 0.707668 | 3 | 0 | 3 |
| FSCN3 | REG3A | 0.707059 | 4 | 0 | 3 |
| FSCN3 | AANAT | 0.703638 | 4 | 0 | 4 |
| FSCN3 | ADAMTS12 | 0.70317 | 4 | 0 | 4 |
| FSCN3 | IL25 | 0.70304 | 6 | 0 | 6 |
For details and further investigation, click here
