| Full name: taste 2 receptor member 8 | Alias Symbol: T2R8|TRB5 | ||
| Type: protein-coding gene | Cytoband: 12p13.2 | ||
| Entrez ID: 50836 | HGNC ID: HGNC:14915 | Ensembl Gene: ENSG00000121314 | OMIM ID: 604794 |
| Drug and gene relationship at DGIdb | |||
Expression of TAS2R8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAS2R8 | 50836 | 221398_at | -0.0429 | 0.9080 | |
| GSE20347 | TAS2R8 | 50836 | 221398_at | -0.0282 | 0.6782 | |
| GSE23400 | TAS2R8 | 50836 | 221398_at | -0.1332 | 0.0003 | |
| GSE26886 | TAS2R8 | 50836 | 221398_at | -0.1043 | 0.2959 | |
| GSE29001 | TAS2R8 | 50836 | 221398_at | -0.1580 | 0.3314 | |
| GSE38129 | TAS2R8 | 50836 | 221398_at | -0.0612 | 0.3870 | |
| GSE45670 | TAS2R8 | 50836 | 221398_at | 0.0330 | 0.7349 | |
| GSE53622 | TAS2R8 | 50836 | 81507 | 0.7653 | 0.0000 | |
| GSE53624 | TAS2R8 | 50836 | 81507 | 1.1939 | 0.0000 | |
| GSE63941 | TAS2R8 | 50836 | 221398_at | -0.0432 | 0.7897 | |
| GSE77861 | TAS2R8 | 50836 | 221398_at | -0.1686 | 0.0672 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TAS2R8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAS2R8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAS2R8 | 50836 | 6 | 2 | 22 | |
| GSE20123 | TAS2R8 | 50836 | 6 | 2 | 22 | |
| GSE43470 | TAS2R8 | 50836 | 9 | 3 | 31 | |
| GSE46452 | TAS2R8 | 50836 | 10 | 1 | 48 | |
| GSE47630 | TAS2R8 | 50836 | 14 | 2 | 24 | |
| GSE54993 | TAS2R8 | 50836 | 1 | 10 | 59 | |
| GSE54994 | TAS2R8 | 50836 | 9 | 2 | 42 | |
| GSE60625 | TAS2R8 | 50836 | 0 | 1 | 10 | |
| GSE74703 | TAS2R8 | 50836 | 9 | 2 | 25 | |
| GSE74704 | TAS2R8 | 50836 | 4 | 1 | 15 | |
| TCGA | TAS2R8 | 50836 | 39 | 7 | 50 |
Total number of gains: 107; Total number of losses: 33; Total Number of normals: 348.
Somatic mutations of TAS2R8:
Generating mutation plots.
Highly correlated genes for TAS2R8:
Showing top 20/610 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAS2R8 | CA8 | 0.705932 | 3 | 0 | 3 |
| TAS2R8 | FAM13C | 0.703754 | 3 | 0 | 3 |
| TAS2R8 | UMOD | 0.684278 | 4 | 0 | 4 |
| TAS2R8 | CLRN1-AS1 | 0.683965 | 4 | 0 | 4 |
| TAS2R8 | TBX10 | 0.683857 | 4 | 0 | 4 |
| TAS2R8 | SLC5A4 | 0.682466 | 4 | 0 | 4 |
| TAS2R8 | CHST4 | 0.681092 | 5 | 0 | 4 |
| TAS2R8 | GML | 0.677471 | 5 | 0 | 5 |
| TAS2R8 | CLCA1 | 0.674917 | 5 | 0 | 5 |
| TAS2R8 | KCNH6 | 0.673514 | 3 | 0 | 3 |
| TAS2R8 | GJB4 | 0.671958 | 5 | 0 | 5 |
| TAS2R8 | BPIFA1 | 0.671268 | 5 | 0 | 5 |
| TAS2R8 | FOXN3-AS2 | 0.668824 | 5 | 0 | 5 |
| TAS2R8 | RNF212 | 0.668626 | 3 | 0 | 3 |
| TAS2R8 | BCAN | 0.665341 | 5 | 0 | 5 |
| TAS2R8 | KCNJ10 | 0.662783 | 5 | 0 | 4 |
| TAS2R8 | PAX8 | 0.662427 | 5 | 0 | 5 |
| TAS2R8 | EPHA5 | 0.660565 | 4 | 0 | 4 |
| TAS2R8 | HHLA1 | 0.660244 | 5 | 0 | 4 |
| TAS2R8 | ARR3 | 0.659278 | 5 | 0 | 5 |
For details and further investigation, click here
