| Full name: ATP binding cassette subfamily C member 12 | Alias Symbol: MRP9 | ||
| Type: protein-coding gene | Cytoband: 16q12.1 | ||
| Entrez ID: 94160 | HGNC ID: HGNC:14640 | Ensembl Gene: ENSG00000140798 | OMIM ID: 607041 |
| Drug and gene relationship at DGIdb | |||
Expression of ABCC12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABCC12 | 94160 | 1553410_a_at | 0.1943 | 0.4098 | |
| GSE26886 | ABCC12 | 94160 | 1553410_a_at | 0.0794 | 0.4616 | |
| GSE45670 | ABCC12 | 94160 | 1553410_a_at | 0.0053 | 0.9589 | |
| GSE53622 | ABCC12 | 94160 | 42481 | 0.2746 | 0.4050 | |
| GSE53624 | ABCC12 | 94160 | 46305 | -0.0647 | 0.6216 | |
| GSE63941 | ABCC12 | 94160 | 1553410_a_at | 0.0363 | 0.8342 | |
| GSE77861 | ABCC12 | 94160 | 1553410_a_at | -0.0736 | 0.4727 | |
| TCGA | ABCC12 | 94160 | RNAseq | -2.9731 | 0.1242 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ABCC12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABCC12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABCC12 | 94160 | 2 | 1 | 27 | |
| GSE20123 | ABCC12 | 94160 | 2 | 1 | 27 | |
| GSE43470 | ABCC12 | 94160 | 2 | 7 | 34 | |
| GSE46452 | ABCC12 | 94160 | 38 | 1 | 20 | |
| GSE47630 | ABCC12 | 94160 | 11 | 7 | 22 | |
| GSE54993 | ABCC12 | 94160 | 2 | 5 | 63 | |
| GSE54994 | ABCC12 | 94160 | 6 | 10 | 37 | |
| GSE60625 | ABCC12 | 94160 | 4 | 0 | 7 | |
| GSE74703 | ABCC12 | 94160 | 2 | 4 | 30 | |
| GSE74704 | ABCC12 | 94160 | 2 | 1 | 17 | |
| TCGA | ABCC12 | 94160 | 29 | 11 | 56 |
Total number of gains: 100; Total number of losses: 48; Total Number of normals: 340.
Somatic mutations of ABCC12:
Generating mutation plots.
Highly correlated genes for ABCC12:
Showing top 20/63 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABCC12 | TTLL2 | 0.707861 | 4 | 0 | 4 |
| ABCC12 | SPP2 | 0.665657 | 3 | 0 | 3 |
| ABCC12 | COL25A1 | 0.653925 | 3 | 0 | 3 |
| ABCC12 | FOXE3 | 0.634552 | 3 | 0 | 3 |
| ABCC12 | DEFB128 | 0.634469 | 3 | 0 | 3 |
| ABCC12 | SLC17A4 | 0.633853 | 3 | 0 | 3 |
| ABCC12 | KRTAP4-11 | 0.627837 | 3 | 0 | 3 |
| ABCC12 | BRPF1 | 0.624193 | 3 | 0 | 3 |
| ABCC12 | BPIFA3 | 0.623121 | 3 | 0 | 3 |
| ABCC12 | SPINT3 | 0.620871 | 4 | 0 | 3 |
| ABCC12 | TAS2R8 | 0.619962 | 3 | 0 | 3 |
| ABCC12 | MFSD12 | 0.618042 | 3 | 0 | 3 |
| ABCC12 | SLC6A19 | 0.617568 | 3 | 0 | 3 |
| ABCC12 | CRH | 0.615714 | 3 | 0 | 3 |
| ABCC12 | OR11A1 | 0.614389 | 3 | 0 | 3 |
| ABCC12 | KRTAP4-8 | 0.61436 | 3 | 0 | 3 |
| ABCC12 | CRYGB | 0.609022 | 4 | 0 | 3 |
| ABCC12 | CCDC54 | 0.603703 | 3 | 0 | 3 |
| ABCC12 | OLIG3 | 0.603196 | 4 | 0 | 3 |
| ABCC12 | DEFB123 | 0.598538 | 4 | 0 | 3 |
For details and further investigation, click here
