SYCN

 

Full name: syncollin Alias Symbol: SYL|FLJ27441
Type: protein-coding gene Cytoband: 19q13.2
Entrez ID: 342898 HGNC ID: HGNC:18442 Ensembl Gene: ENSG00000179751 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of SYCN:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SYCN 342898 229995_at -0.0287 0.9264
GSE26886 SYCN 342898 229995_at 0.0787 0.5372
GSE45670 SYCN 342898 229995_at 0.0873 0.3253
GSE53622 SYCN 342898 65341 0.6173 0.0000
GSE53624 SYCN 342898 65341 0.5253 0.0000
GSE63941 SYCN 342898 229995_at 0.1375 0.2973
GSE77861 SYCN 342898 229995_at -0.0455 0.6964
GSE97050 SYCN 342898 A_24_P39928 0.1343 0.5862
TCGA SYCN 342898 RNAseq -3.4537 0.0001

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by SYCN expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SYCN:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SYCN 342898 7 4 19
GSE20123 SYCN 342898 7 3 20
GSE43470 SYCN 342898 4 11 28
GSE46452 SYCN 342898 47 2 10
GSE47630 SYCN 342898 9 5 26
GSE54993 SYCN 342898 17 3 50
GSE54994 SYCN 342898 7 9 37
GSE60625 SYCN 342898 9 0 2
GSE74703 SYCN 342898 4 7 25
GSE74704 SYCN 342898 7 1 12
TCGA SYCN 342898 14 16 66

Total number of gains: 132; Total number of losses: 61; Total Number of normals: 295.  


 

Somatic mutations of SYCN:

 

Generating mutation plots.

 

Highly correlated genes for SYCN:

 

Showing top 20/281 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SYCNKRTAP5-70.877212303
SYCNKRTAP10-120.848166303
SYCNF2RL30.830252303
SYCNXRCC20.820729303
SYCNBMP8B0.795387303
SYCNFOXE30.791884303
SYCNDCDC10.782753303
SYCNGCM20.780028303
SYCNGHSR0.775963303
SYCNTNFAIP8L10.770347303
SYCNALPP0.770286303
SYCNSTRC0.769654303
SYCNBFSP2-AS10.759209303
SYCNPLA2G2C0.758051303
SYCNMRPS160.750625303
SYCNC19orf440.746131303
SYCNOR2A50.736151303
SYCNOR4D60.730775303
SYCNDEFB1280.729874303
SYCNNBPF30.725383303

For details and further investigation, click here