DEFB127

 

Full name: defensin beta 127 Alias Symbol: bA530N10.2|DEF-27
Type: protein-coding gene Cytoband: 20p13
Entrez ID: 140850 HGNC ID: HGNC:16206 Ensembl Gene: ENSG00000088782 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of DEFB127:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DEFB127 140850 233343_at 0.0009 0.9981
GSE26886 DEFB127 140850 233343_at 0.0413 0.6234
GSE45670 DEFB127 140850 233343_at 0.0230 0.7756
GSE53622 DEFB127 140850 48019 0.0351 0.7185
GSE53624 DEFB127 140850 48019 -0.2178 0.0792
GSE63941 DEFB127 140850 233343_at 0.1199 0.3941
GSE77861 DEFB127 140850 233343_at -0.0662 0.3889

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by DEFB127 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of DEFB127:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DEFB127 140850 12 4 14
GSE20123 DEFB127 140850 13 4 13
GSE43470 DEFB127 140850 11 1 31
GSE46452 DEFB127 140850 26 1 32
GSE47630 DEFB127 140850 19 4 17
GSE54993 DEFB127 140850 2 15 53
GSE54994 DEFB127 140850 24 2 27
GSE60625 DEFB127 140850 0 0 11
GSE74703 DEFB127 140850 10 1 25
GSE74704 DEFB127 140850 8 2 10
TCGA DEFB127 140850 41 11 44

Total number of gains: 166; Total number of losses: 45; Total Number of normals: 277.  

 

Somatic mutations of DEFB127:

 

Generating mutation plots.

 

Highly correlated genes for DEFB127:

 

Showing all 7 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DEFB127IFNA140.588356503
DEFB127LINC004210.554353403
DEFB127KCNH40.536573403
DEFB127TTLL20.511619403
DEFB127DSCR80.511154403
DEFB127SPINT30.508616503
DEFB127LDHAL6A0.501764503

For details and further investigation, click here