| Full name: tubulin tyrosine ligase like 2 | Alias Symbol: NYD-TSPG|dJ366N23.3 | ||
| Type: protein-coding gene | Cytoband: 6q27 | ||
| Entrez ID: 83887 | HGNC ID: HGNC:21211 | Ensembl Gene: ENSG00000120440 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TTLL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TTLL2 | 83887 | 223998_at | 0.1971 | 0.4565 | |
| GSE26886 | TTLL2 | 83887 | 223998_at | -0.0294 | 0.8139 | |
| GSE45670 | TTLL2 | 83887 | 223998_at | 0.1216 | 0.2314 | |
| GSE53622 | TTLL2 | 83887 | 50530 | 0.4880 | 0.0258 | |
| GSE53624 | TTLL2 | 83887 | 37491 | 0.0791 | 0.6769 | |
| GSE63941 | TTLL2 | 83887 | 223998_at | 0.0044 | 0.9797 | |
| GSE77861 | TTLL2 | 83887 | 223998_at | -0.1458 | 0.1379 | |
| TCGA | TTLL2 | 83887 | RNAseq | 0.2881 | 0.7079 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TTLL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TTLL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TTLL2 | 83887 | 4 | 6 | 20 | |
| GSE20123 | TTLL2 | 83887 | 4 | 6 | 20 | |
| GSE43470 | TTLL2 | 83887 | 3 | 0 | 40 | |
| GSE46452 | TTLL2 | 83887 | 3 | 10 | 46 | |
| GSE47630 | TTLL2 | 83887 | 7 | 7 | 26 | |
| GSE54993 | TTLL2 | 83887 | 4 | 3 | 63 | |
| GSE54994 | TTLL2 | 83887 | 10 | 8 | 35 | |
| GSE60625 | TTLL2 | 83887 | 1 | 1 | 9 | |
| GSE74703 | TTLL2 | 83887 | 3 | 0 | 33 | |
| GSE74704 | TTLL2 | 83887 | 2 | 3 | 15 | |
| TCGA | TTLL2 | 83887 | 14 | 21 | 61 |
Total number of gains: 55; Total number of losses: 65; Total Number of normals: 368.
Somatic mutations of TTLL2:
Generating mutation plots.
Highly correlated genes for TTLL2:
Showing top 20/73 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TTLL2 | ABCC12 | 0.707861 | 4 | 0 | 4 |
| TTLL2 | FOXP4 | 0.702156 | 3 | 0 | 3 |
| TTLL2 | CDX1 | 0.673967 | 3 | 0 | 3 |
| TTLL2 | UTS2R | 0.644113 | 4 | 0 | 3 |
| TTLL2 | LTA | 0.640104 | 3 | 0 | 3 |
| TTLL2 | SLC17A4 | 0.636536 | 3 | 0 | 3 |
| TTLL2 | DEFB128 | 0.633276 | 3 | 0 | 3 |
| TTLL2 | OR51M1 | 0.62929 | 5 | 0 | 4 |
| TTLL2 | OR6C74 | 0.626827 | 3 | 0 | 3 |
| TTLL2 | AQP8 | 0.606476 | 4 | 0 | 3 |
| TTLL2 | ADAM12 | 0.605163 | 4 | 0 | 3 |
| TTLL2 | GAGE1 | 0.604066 | 4 | 0 | 3 |
| TTLL2 | SPEG | 0.597318 | 3 | 0 | 3 |
| TTLL2 | CACNG7 | 0.597118 | 3 | 0 | 3 |
| TTLL2 | C6orf201 | 0.593849 | 3 | 0 | 3 |
| TTLL2 | RAB4B | 0.591213 | 3 | 0 | 3 |
| TTLL2 | EIF5AL1 | 0.59061 | 3 | 0 | 3 |
| TTLL2 | CD4 | 0.586713 | 3 | 0 | 3 |
| TTLL2 | NLRP4 | 0.586525 | 3 | 0 | 3 |
| TTLL2 | GDPD4 | 0.585055 | 3 | 0 | 3 |
For details and further investigation, click here
