| Full name: potassium voltage-gated channel subfamily H member 4 | Alias Symbol: Kv12.3|elk1 | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 23415 | HGNC ID: HGNC:6253 | Ensembl Gene: ENSG00000089558 | OMIM ID: 604528 |
| Drug and gene relationship at DGIdb | |||
Expression of KCNH4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KCNH4 | 23415 | 220802_at | 0.1322 | 0.5762 | |
| GSE20347 | KCNH4 | 23415 | 220802_at | 0.0228 | 0.8113 | |
| GSE23400 | KCNH4 | 23415 | 220802_at | -0.0579 | 0.1007 | |
| GSE26886 | KCNH4 | 23415 | 220802_at | 0.1217 | 0.3943 | |
| GSE29001 | KCNH4 | 23415 | 220802_at | -0.0396 | 0.8221 | |
| GSE38129 | KCNH4 | 23415 | 220802_at | -0.0647 | 0.4550 | |
| GSE45670 | KCNH4 | 23415 | 220802_at | 0.0387 | 0.7151 | |
| GSE63941 | KCNH4 | 23415 | 220802_at | 0.1509 | 0.2806 | |
| GSE77861 | KCNH4 | 23415 | 220802_at | -0.1502 | 0.1950 | |
| GSE97050 | KCNH4 | 23415 | A_23_P124988 | -0.0952 | 0.7136 | |
| TCGA | KCNH4 | 23415 | RNAseq | -1.1389 | 0.0166 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by KCNH4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of KCNH4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KCNH4 | 23415 | 6 | 2 | 22 | |
| GSE20123 | KCNH4 | 23415 | 6 | 2 | 22 | |
| GSE43470 | KCNH4 | 23415 | 1 | 2 | 40 | |
| GSE46452 | KCNH4 | 23415 | 34 | 0 | 25 | |
| GSE47630 | KCNH4 | 23415 | 8 | 1 | 31 | |
| GSE54993 | KCNH4 | 23415 | 3 | 4 | 63 | |
| GSE54994 | KCNH4 | 23415 | 8 | 5 | 40 | |
| GSE60625 | KCNH4 | 23415 | 4 | 0 | 7 | |
| GSE74703 | KCNH4 | 23415 | 1 | 1 | 34 | |
| GSE74704 | KCNH4 | 23415 | 4 | 1 | 15 | |
| TCGA | KCNH4 | 23415 | 23 | 6 | 67 |
Total number of gains: 98; Total number of losses: 24; Total Number of normals: 366.
Somatic mutations of KCNH4:
Generating mutation plots.
Highly correlated genes for KCNH4:
Showing top 20/707 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KCNH4 | PGC | 0.733343 | 3 | 0 | 3 |
| KCNH4 | MEPE | 0.727631 | 4 | 0 | 4 |
| KCNH4 | ARVCF | 0.721437 | 5 | 0 | 5 |
| KCNH4 | CDH7 | 0.706136 | 5 | 0 | 4 |
| KCNH4 | NPY2R | 0.695341 | 4 | 0 | 4 |
| KCNH4 | MAT1A | 0.690804 | 7 | 0 | 7 |
| KCNH4 | PDE6B | 0.685498 | 3 | 0 | 3 |
| KCNH4 | SIX6 | 0.683795 | 6 | 0 | 6 |
| KCNH4 | FAM71A | 0.681719 | 3 | 0 | 3 |
| KCNH4 | IFNA17 | 0.679743 | 4 | 0 | 4 |
| KCNH4 | PKD2L1 | 0.678962 | 5 | 0 | 5 |
| KCNH4 | SEZ6L2 | 0.67569 | 3 | 0 | 3 |
| KCNH4 | GPBAR1 | 0.671227 | 4 | 0 | 4 |
| KCNH4 | KIR3DL3 | 0.669313 | 5 | 0 | 4 |
| KCNH4 | HAP1 | 0.669159 | 4 | 0 | 4 |
| KCNH4 | GDF10 | 0.666274 | 3 | 0 | 3 |
| KCNH4 | RNF123 | 0.663905 | 3 | 0 | 3 |
| KCNH4 | OR4D2 | 0.661752 | 3 | 0 | 3 |
| KCNH4 | FMR1NB | 0.661621 | 3 | 0 | 3 |
| KCNH4 | AOC2 | 0.658873 | 5 | 0 | 4 |
For details and further investigation, click here
