| Full name: lactate dehydrogenase A like 6A | Alias Symbol: MGC23940|LDH6A | ||
| Type: protein-coding gene | Cytoband: 11p15.1 | ||
| Entrez ID: 160287 | HGNC ID: HGNC:28335 | Ensembl Gene: ENSG00000166800 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LDHAL6A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LDHAL6A | 160287 | 1553888_at | -0.0275 | 0.9305 | |
| GSE26886 | LDHAL6A | 160287 | 1553888_at | -0.5000 | 0.0003 | |
| GSE45670 | LDHAL6A | 160287 | 1553888_at | -0.0053 | 0.9630 | |
| GSE53622 | LDHAL6A | 160287 | 8523 | 0.7528 | 0.0000 | |
| GSE53624 | LDHAL6A | 160287 | 8523 | 0.4962 | 0.0000 | |
| GSE63941 | LDHAL6A | 160287 | 1553888_at | 0.0015 | 0.9928 | |
| GSE77861 | LDHAL6A | 160287 | 1553888_at | -0.2513 | 0.0429 | |
| GSE97050 | LDHAL6A | 160287 | A_33_P3236441 | 0.2764 | 0.2261 | |
| SRP007169 | LDHAL6A | 160287 | RNAseq | 0.8666 | 0.3065 | |
| SRP133303 | LDHAL6A | 160287 | RNAseq | -0.2851 | 0.0981 | |
| SRP193095 | LDHAL6A | 160287 | RNAseq | 0.1005 | 0.5696 | |
| TCGA | LDHAL6A | 160287 | RNAseq | -1.0131 | 0.0330 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by LDHAL6A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LDHAL6A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LDHAL6A | 160287 | 0 | 10 | 20 | |
| GSE20123 | LDHAL6A | 160287 | 0 | 10 | 20 | |
| GSE43470 | LDHAL6A | 160287 | 1 | 5 | 37 | |
| GSE46452 | LDHAL6A | 160287 | 7 | 5 | 47 | |
| GSE47630 | LDHAL6A | 160287 | 3 | 10 | 27 | |
| GSE54993 | LDHAL6A | 160287 | 3 | 0 | 67 | |
| GSE54994 | LDHAL6A | 160287 | 2 | 13 | 38 | |
| GSE60625 | LDHAL6A | 160287 | 0 | 0 | 11 | |
| GSE74703 | LDHAL6A | 160287 | 1 | 3 | 32 | |
| GSE74704 | LDHAL6A | 160287 | 0 | 9 | 11 | |
| TCGA | LDHAL6A | 160287 | 11 | 29 | 56 |
Total number of gains: 28; Total number of losses: 94; Total Number of normals: 366.
Somatic mutations of LDHAL6A:
Generating mutation plots.
Highly correlated genes for LDHAL6A:
Showing top 20/159 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LDHAL6A | KANK3 | 0.846312 | 4 | 0 | 4 |
| LDHAL6A | VHL | 0.760733 | 3 | 0 | 3 |
| LDHAL6A | C5orf17 | 0.741907 | 3 | 0 | 3 |
| LDHAL6A | SERHL2 | 0.732391 | 3 | 0 | 3 |
| LDHAL6A | KLF17 | 0.731285 | 4 | 0 | 3 |
| LDHAL6A | KCNH3 | 0.72221 | 3 | 0 | 3 |
| LDHAL6A | ZNF763 | 0.711941 | 4 | 0 | 3 |
| LDHAL6A | MATN1 | 0.708333 | 3 | 0 | 3 |
| LDHAL6A | FFAR2 | 0.706304 | 3 | 0 | 3 |
| LDHAL6A | C9orf153 | 0.702732 | 3 | 0 | 3 |
| LDHAL6A | AICDA | 0.702493 | 3 | 0 | 3 |
| LDHAL6A | OR1J4 | 0.701082 | 4 | 0 | 3 |
| LDHAL6A | DDC | 0.69995 | 3 | 0 | 3 |
| LDHAL6A | HGFAC | 0.694101 | 3 | 0 | 3 |
| LDHAL6A | TBC1D10B | 0.691282 | 4 | 0 | 3 |
| LDHAL6A | CNPY1 | 0.686154 | 3 | 0 | 3 |
| LDHAL6A | B3GNT8 | 0.685961 | 3 | 0 | 3 |
| LDHAL6A | CSMD2 | 0.685787 | 4 | 0 | 3 |
| LDHAL6A | TNR | 0.684603 | 4 | 0 | 4 |
| LDHAL6A | TAS2R31 | 0.684153 | 3 | 0 | 3 |
For details and further investigation, click here
