FOLR1

 

Full name: folate receptor alpha Alias Symbol: FRα
Type: protein-coding gene Cytoband: 11q13.4
Entrez ID: 2348 HGNC ID: HGNC:3791 Ensembl Gene: ENSG00000110195 OMIM ID: 136430
Drug and gene relationship at DGIdb

 

Expression of FOLR1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 FOLR1 2348 11261 -0.6496 0.0001
GSE53624 FOLR1 2348 11261 -0.4940 0.0003
GSE97050 FOLR1 2348 A_23_P53176 0.0390 0.9269
SRP133303 FOLR1 2348 RNAseq -2.4645 0.0012
TCGA FOLR1 2348 RNAseq -2.5608 0.0017

Upregulated datasets: 0; Downregulated datasets: 2.  

 

Survival by FOLR1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of FOLR1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FOLR1 2348 10 7 13
GSE20123 FOLR1 2348 10 7 13
GSE43470 FOLR1 2348 9 4 30
GSE46452 FOLR1 2348 12 17 30
GSE47630 FOLR1 2348 10 10 20
GSE54993 FOLR1 2348 7 3 60
GSE54994 FOLR1 2348 12 12 29
GSE60625 FOLR1 2348 0 7 4
GSE74703 FOLR1 2348 7 3 26
GSE74704 FOLR1 2348 7 4 9
TCGA FOLR1 2348 36 20 40

Total number of gains: 120; Total number of losses: 94; Total Number of normals: 274.  

 

Somatic mutations of FOLR1:

 

Generating mutation plots.

 

Highly correlated genes for FOLR1:

 

Showing all 8 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FOLR1FOLR30.906185303
FOLR1TFF10.737509303
FOLR1LRRC310.697492303
FOLR1AZGP10.677381303
FOLR1LGALS90.649349303
FOLR1SPDEF0.639127303
FOLR1LRRC260.613917303
FOLR1DCAF8L20.598853303

For details and further investigation, click here