| Full name: folate receptor gamma | Alias Symbol: FR-G|FRγ | ||
| Type: protein-coding gene | Cytoband: 11q13.4 | ||
| Entrez ID: 2352 | HGNC ID: HGNC:3795 | Ensembl Gene: ENSG00000110203 | OMIM ID: 602469 |
| Drug and gene relationship at DGIdb | |||
Expression of FOLR3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FOLR3 | 2352 | 206371_at | 0.3614 | 0.4196 | |
| GSE20347 | FOLR3 | 2352 | 206371_at | -0.0005 | 0.9962 | |
| GSE23400 | FOLR3 | 2352 | 206371_at | 0.0169 | 0.7349 | |
| GSE26886 | FOLR3 | 2352 | 206371_at | 0.6667 | 0.0026 | |
| GSE29001 | FOLR3 | 2352 | 206371_at | -0.0337 | 0.8737 | |
| GSE38129 | FOLR3 | 2352 | 206371_at | 0.0504 | 0.4262 | |
| GSE45670 | FOLR3 | 2352 | 206371_at | 0.8021 | 0.0476 | |
| GSE53622 | FOLR3 | 2352 | 141058 | -0.4930 | 0.0108 | |
| GSE53624 | FOLR3 | 2352 | 141058 | -0.1803 | 0.3271 | |
| GSE63941 | FOLR3 | 2352 | 206371_at | 0.3623 | 0.3462 | |
| GSE77861 | FOLR3 | 2352 | 206371_at | 0.1152 | 0.3921 | |
| GSE97050 | FOLR3 | 2352 | A_24_P252996 | 0.1938 | 0.6450 | |
| SRP219564 | FOLR3 | 2352 | RNAseq | 3.6252 | 0.0006 | |
| TCGA | FOLR3 | 2352 | RNAseq | 3.4692 | 0.0005 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by FOLR3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FOLR3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FOLR3 | 2352 | 10 | 7 | 13 | |
| GSE20123 | FOLR3 | 2352 | 10 | 7 | 13 | |
| GSE43470 | FOLR3 | 2352 | 9 | 4 | 30 | |
| GSE46452 | FOLR3 | 2352 | 12 | 17 | 30 | |
| GSE47630 | FOLR3 | 2352 | 10 | 10 | 20 | |
| GSE54993 | FOLR3 | 2352 | 7 | 3 | 60 | |
| GSE54994 | FOLR3 | 2352 | 14 | 11 | 28 | |
| GSE60625 | FOLR3 | 2352 | 0 | 7 | 4 | |
| GSE74703 | FOLR3 | 2352 | 7 | 3 | 26 | |
| GSE74704 | FOLR3 | 2352 | 7 | 4 | 9 | |
| TCGA | FOLR3 | 2352 | 36 | 20 | 40 |
Total number of gains: 122; Total number of losses: 93; Total Number of normals: 273.
Somatic mutations of FOLR3:
Generating mutation plots.
Highly correlated genes for FOLR3:
Showing top 20/249 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FOLR3 | FOLR1 | 0.906185 | 3 | 0 | 3 |
| FOLR3 | PRKAR1B | 0.757155 | 3 | 0 | 3 |
| FOLR3 | SCLY | 0.746778 | 3 | 0 | 3 |
| FOLR3 | EGR4 | 0.72493 | 3 | 0 | 3 |
| FOLR3 | AGAP2 | 0.717098 | 3 | 0 | 3 |
| FOLR3 | ELAVL2 | 0.716587 | 3 | 0 | 3 |
| FOLR3 | SFTPD | 0.715332 | 3 | 0 | 3 |
| FOLR3 | STRIP2 | 0.702746 | 3 | 0 | 3 |
| FOLR3 | ATG16L1 | 0.690682 | 3 | 0 | 3 |
| FOLR3 | NPW | 0.685446 | 3 | 0 | 3 |
| FOLR3 | AOC2 | 0.666229 | 3 | 0 | 3 |
| FOLR3 | CRYBB1 | 0.665697 | 3 | 0 | 3 |
| FOLR3 | RUNX1-IT1 | 0.664541 | 4 | 0 | 4 |
| FOLR3 | OR3A3 | 0.662452 | 3 | 0 | 3 |
| FOLR3 | GRK4 | 0.660546 | 3 | 0 | 3 |
| FOLR3 | IGSF8 | 0.654725 | 4 | 0 | 4 |
| FOLR3 | MRGBP | 0.654461 | 3 | 0 | 3 |
| FOLR3 | GNG4 | 0.653361 | 3 | 0 | 3 |
| FOLR3 | DIAPH3 | 0.649266 | 4 | 0 | 3 |
| FOLR3 | STK32C | 0.640895 | 3 | 0 | 3 |
For details and further investigation, click here
