| Full name: alpha-2-glycoprotein 1, zinc-binding | Alias Symbol: ZA2G|ZAG | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 563 | HGNC ID: HGNC:910 | Ensembl Gene: ENSG00000160862 | OMIM ID: 194460 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of AZGP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AZGP1 | 563 | 209309_at | -2.8127 | 0.1551 | |
| GSE20347 | AZGP1 | 563 | 209309_at | -0.1309 | 0.6346 | |
| GSE23400 | AZGP1 | 563 | 209309_at | -0.9786 | 0.0000 | |
| GSE26886 | AZGP1 | 563 | 209309_at | 0.2091 | 0.1055 | |
| GSE29001 | AZGP1 | 563 | 209309_at | -0.1367 | 0.7936 | |
| GSE38129 | AZGP1 | 563 | 209309_at | -0.9314 | 0.0202 | |
| GSE45670 | AZGP1 | 563 | 209309_at | -1.2863 | 0.0504 | |
| GSE53622 | AZGP1 | 563 | 102402 | -1.6317 | 0.0000 | |
| GSE53624 | AZGP1 | 563 | 102402 | -1.8414 | 0.0000 | |
| GSE63941 | AZGP1 | 563 | 209309_at | 0.2181 | 0.5924 | |
| GSE77861 | AZGP1 | 563 | 209309_at | 0.0814 | 0.5475 | |
| GSE97050 | AZGP1 | 563 | A_23_P71270 | -0.0530 | 0.8989 | |
| SRP133303 | AZGP1 | 563 | RNAseq | -4.9615 | 0.0000 | |
| TCGA | AZGP1 | 563 | RNAseq | -1.9711 | 0.0005 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by AZGP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AZGP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AZGP1 | 563 | 13 | 0 | 17 | |
| GSE20123 | AZGP1 | 563 | 13 | 0 | 17 | |
| GSE43470 | AZGP1 | 563 | 6 | 2 | 35 | |
| GSE46452 | AZGP1 | 563 | 11 | 1 | 47 | |
| GSE47630 | AZGP1 | 563 | 7 | 3 | 30 | |
| GSE54993 | AZGP1 | 563 | 1 | 9 | 60 | |
| GSE54994 | AZGP1 | 563 | 16 | 3 | 34 | |
| GSE60625 | AZGP1 | 563 | 0 | 0 | 11 | |
| GSE74703 | AZGP1 | 563 | 6 | 1 | 29 | |
| GSE74704 | AZGP1 | 563 | 9 | 0 | 11 | |
| TCGA | AZGP1 | 563 | 52 | 6 | 38 |
Total number of gains: 134; Total number of losses: 25; Total Number of normals: 329.
Somatic mutations of AZGP1:
Generating mutation plots.
Highly correlated genes for AZGP1:
Showing top 20/70 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AZGP1 | C6orf58 | 0.843323 | 5 | 0 | 5 |
| AZGP1 | LRRC26 | 0.837027 | 3 | 0 | 3 |
| AZGP1 | BPIFB1 | 0.819281 | 6 | 0 | 6 |
| AZGP1 | MUC5B | 0.755632 | 9 | 0 | 8 |
| AZGP1 | SCGB3A1 | 0.745706 | 7 | 0 | 7 |
| AZGP1 | GJB1 | 0.730049 | 3 | 0 | 3 |
| AZGP1 | GP2 | 0.720309 | 6 | 0 | 6 |
| AZGP1 | AGR3 | 0.717403 | 4 | 0 | 4 |
| AZGP1 | PIP | 0.710618 | 5 | 0 | 5 |
| AZGP1 | CHRM1 | 0.708539 | 4 | 0 | 4 |
| AZGP1 | PIGR | 0.70526 | 6 | 0 | 5 |
| AZGP1 | ZG16B | 0.701085 | 7 | 0 | 5 |
| AZGP1 | TSPAN8 | 0.699479 | 8 | 0 | 7 |
| AZGP1 | SCGB2A1 | 0.694683 | 6 | 0 | 5 |
| AZGP1 | SCGB2A2 | 0.694586 | 7 | 0 | 6 |
| AZGP1 | MUC7 | 0.694039 | 5 | 0 | 4 |
| AZGP1 | TFF3 | 0.6892 | 8 | 0 | 5 |
| AZGP1 | FOLR1 | 0.677381 | 3 | 0 | 3 |
| AZGP1 | TFF1 | 0.675479 | 7 | 0 | 6 |
| AZGP1 | PROM1 | 0.66798 | 10 | 0 | 8 |
For details and further investigation, click here
