| Full name: leucine rich repeat containing 31 | Alias Symbol: FLJ23259 | ||
| Type: protein-coding gene | Cytoband: 3q26.2 | ||
| Entrez ID: 79782 | HGNC ID: HGNC:26261 | Ensembl Gene: ENSG00000114248 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC31:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC31 | 79782 | 220622_at | -0.4119 | 0.2998 | |
| GSE20347 | LRRC31 | 79782 | 220622_at | -0.0240 | 0.6778 | |
| GSE23400 | LRRC31 | 79782 | 220622_at | -0.0841 | 0.0341 | |
| GSE26886 | LRRC31 | 79782 | 220622_at | -0.0200 | 0.8891 | |
| GSE29001 | LRRC31 | 79782 | 220622_at | -0.1407 | 0.3886 | |
| GSE38129 | LRRC31 | 79782 | 220622_at | -0.1764 | 0.2404 | |
| GSE45670 | LRRC31 | 79782 | 220622_at | -0.2430 | 0.4493 | |
| GSE53622 | LRRC31 | 79782 | 151050 | -0.9932 | 0.0023 | |
| GSE53624 | LRRC31 | 79782 | 151050 | -1.7511 | 0.0000 | |
| GSE63941 | LRRC31 | 79782 | 220622_at | -0.1603 | 0.2874 | |
| GSE77861 | LRRC31 | 79782 | 220622_at | -0.0146 | 0.8613 | |
| GSE97050 | LRRC31 | 79782 | A_24_P281036 | -0.1192 | 0.5745 | |
| SRP133303 | LRRC31 | 79782 | RNAseq | -2.7735 | 0.0081 | |
| TCGA | LRRC31 | 79782 | RNAseq | -4.6815 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by LRRC31 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC31:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC31 | 79782 | 22 | 0 | 8 | |
| GSE20123 | LRRC31 | 79782 | 22 | 0 | 8 | |
| GSE43470 | LRRC31 | 79782 | 24 | 0 | 19 | |
| GSE46452 | LRRC31 | 79782 | 19 | 1 | 39 | |
| GSE47630 | LRRC31 | 79782 | 27 | 2 | 11 | |
| GSE54993 | LRRC31 | 79782 | 1 | 14 | 55 | |
| GSE54994 | LRRC31 | 79782 | 41 | 0 | 12 | |
| GSE60625 | LRRC31 | 79782 | 0 | 6 | 5 | |
| GSE74703 | LRRC31 | 79782 | 20 | 0 | 16 | |
| GSE74704 | LRRC31 | 79782 | 14 | 0 | 6 | |
| TCGA | LRRC31 | 79782 | 80 | 0 | 16 |
Total number of gains: 270; Total number of losses: 23; Total Number of normals: 195.
Somatic mutations of LRRC31:
Generating mutation plots.
Highly correlated genes for LRRC31:
Showing top 20/163 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC31 | SLC5A4 | 0.799643 | 3 | 0 | 3 |
| LRRC31 | LCT | 0.753508 | 4 | 0 | 4 |
| LRRC31 | BTBD9 | 0.737405 | 3 | 0 | 3 |
| LRRC31 | RNF17 | 0.732592 | 3 | 0 | 3 |
| LRRC31 | RALYL | 0.726283 | 3 | 0 | 3 |
| LRRC31 | TAS2R3 | 0.724051 | 4 | 0 | 4 |
| LRRC31 | LMAN1L | 0.721165 | 3 | 0 | 3 |
| LRRC31 | TFF1 | 0.715146 | 8 | 0 | 7 |
| LRRC31 | KLHL35 | 0.703691 | 3 | 0 | 3 |
| LRRC31 | FOLR1 | 0.697492 | 3 | 0 | 3 |
| LRRC31 | KSR1 | 0.696874 | 4 | 0 | 4 |
| LRRC31 | NPY2R | 0.694448 | 3 | 0 | 3 |
| LRRC31 | CHRNB4 | 0.691675 | 3 | 0 | 3 |
| LRRC31 | AGR3 | 0.691222 | 5 | 0 | 4 |
| LRRC31 | SLC17A1 | 0.688628 | 3 | 0 | 3 |
| LRRC31 | PRAMEF12 | 0.688265 | 3 | 0 | 3 |
| LRRC31 | NOL4 | 0.682581 | 3 | 0 | 3 |
| LRRC31 | GRM6 | 0.670487 | 4 | 0 | 3 |
| LRRC31 | ENTPD8 | 0.668792 | 3 | 0 | 3 |
| LRRC31 | GRID2 | 0.665951 | 3 | 0 | 3 |
For details and further investigation, click here
