| Full name: leucine rich repeat containing 26 | Alias Symbol: bA350O14.10|OTTHUMG00000020980 | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 389816 | HGNC ID: HGNC:31409 | Ensembl Gene: ENSG00000184709 | OMIM ID: 613505 |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC26:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | LRRC26 | 389816 | 52263 | -1.7658 | 0.0000 | |
| GSE53624 | LRRC26 | 389816 | 52263 | -2.1348 | 0.0000 | |
| GSE97050 | LRRC26 | 389816 | A_33_P3269844 | -0.1632 | 0.6528 | |
| SRP133303 | LRRC26 | 389816 | RNAseq | -4.7801 | 0.0000 | |
| SRP159526 | LRRC26 | 389816 | RNAseq | -2.7544 | 0.0312 | |
| TCGA | LRRC26 | 389816 | RNAseq | -2.1524 | 0.0009 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by LRRC26 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC26:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC26 | 389816 | 5 | 7 | 18 | |
| GSE20123 | LRRC26 | 389816 | 5 | 7 | 18 | |
| GSE43470 | LRRC26 | 389816 | 3 | 7 | 33 | |
| GSE46452 | LRRC26 | 389816 | 6 | 13 | 40 | |
| GSE47630 | LRRC26 | 389816 | 6 | 15 | 19 | |
| GSE54993 | LRRC26 | 389816 | 3 | 3 | 64 | |
| GSE54994 | LRRC26 | 389816 | 12 | 8 | 33 | |
| GSE60625 | LRRC26 | 389816 | 0 | 0 | 11 | |
| GSE74703 | LRRC26 | 389816 | 3 | 5 | 28 | |
| GSE74704 | LRRC26 | 389816 | 3 | 5 | 12 | |
| TCGA | LRRC26 | 389816 | 29 | 23 | 44 |
Total number of gains: 75; Total number of losses: 93; Total Number of normals: 320.
Somatic mutations of LRRC26:
Generating mutation plots.
Highly correlated genes for LRRC26:
Showing top 20/205 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC26 | AZGP1 | 0.837027 | 3 | 0 | 3 |
| LRRC26 | SCGB3A1 | 0.832618 | 3 | 0 | 3 |
| LRRC26 | ZG16B | 0.826152 | 3 | 0 | 3 |
| LRRC26 | MUC7 | 0.781317 | 3 | 0 | 3 |
| LRRC26 | MUC5B | 0.781178 | 3 | 0 | 3 |
| LRRC26 | FAM3D | 0.778872 | 3 | 0 | 3 |
| LRRC26 | BPIFB2 | 0.774529 | 3 | 0 | 3 |
| LRRC26 | PIGR | 0.765256 | 3 | 0 | 3 |
| LRRC26 | C6orf58 | 0.75502 | 3 | 0 | 3 |
| LRRC26 | BPIFB1 | 0.739009 | 3 | 0 | 3 |
| LRRC26 | CXCL17 | 0.736071 | 3 | 0 | 3 |
| LRRC26 | ST6GALNAC1 | 0.731241 | 3 | 0 | 3 |
| LRRC26 | STATH | 0.731067 | 3 | 0 | 3 |
| LRRC26 | MSMB | 0.730359 | 3 | 0 | 3 |
| LRRC26 | GJB1 | 0.716093 | 3 | 0 | 3 |
| LRRC26 | GCNT3 | 0.706046 | 3 | 0 | 3 |
| LRRC26 | TCN1 | 0.70503 | 3 | 0 | 3 |
| LRRC26 | PGAP3 | 0.699858 | 3 | 0 | 3 |
| LRRC26 | ELN | 0.69788 | 3 | 0 | 3 |
| LRRC26 | PRB1 | 0.686509 | 3 | 0 | 3 |
For details and further investigation, click here
