PXT1

 

Full name: peroxisomal testis enriched protein 1 Alias Symbol: STEPP
Type: protein-coding gene Cytoband: 6p21.31
Entrez ID: 222659 HGNC ID: HGNC:18312 Ensembl Gene: ENSG00000179165 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of PXT1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PXT1 222659 1552599_at 0.0554 0.8108
GSE26886 PXT1 222659 1552599_at -0.0352 0.6854
GSE45670 PXT1 222659 1552599_at -0.0213 0.8521
GSE53622 PXT1 222659 12591 0.4044 0.0269
GSE53624 PXT1 222659 12591 0.1724 0.0161
GSE63941 PXT1 222659 1552599_at -0.1855 0.1657
GSE77861 PXT1 222659 1552599_at -0.0950 0.3219
TCGA PXT1 222659 RNAseq 1.3961 0.0380

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by PXT1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PXT1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PXT1 222659 6 0 24
GSE20123 PXT1 222659 6 0 24
GSE43470 PXT1 222659 5 1 37
GSE46452 PXT1 222659 2 9 48
GSE47630 PXT1 222659 8 4 28
GSE54993 PXT1 222659 3 1 66
GSE54994 PXT1 222659 10 5 38
GSE60625 PXT1 222659 1 0 10
GSE74703 PXT1 222659 5 0 31
GSE74704 PXT1 222659 3 0 17
TCGA PXT1 222659 15 15 66

Total number of gains: 64; Total number of losses: 35; Total Number of normals: 389.  

 

Somatic mutations of PXT1:

 

Generating mutation plots.

 

Highly correlated genes for PXT1:

 

Showing all 11 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PXT1GLDC0.645331303
PXT1SRA10.641648303
PXT1LINC012810.626872303
PXT1SLC9C20.585019403
PXT1YIPF50.574271303
PXT1TMEM132B0.568815303
PXT1LINC008800.561399303
PXT1KCNQ30.549987303
PXT1OR2C30.534876403
PXT1KRTAP1-50.51748403
PXT1ATP1B40.503308503

For details and further investigation, click here