OR2C3

 

Full name: olfactory receptor family 2 subfamily C member 3 Alias Symbol: OST742
Type: protein-coding gene Cytoband: 1q44
Entrez ID: 81472 HGNC ID: HGNC:15005 Ensembl Gene: ENSG00000196242 OMIM ID: 
Drug and gene relationship at DGIdb

 

OR2C3 involved pathways:

KEGG pathway Description View
hsa04740Olfactory transduction

 

Expression of OR2C3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 OR2C3 81472 1555018_at 0.0624 0.7856
GSE26886 OR2C3 81472 1555018_at 0.0339 0.7709
GSE45670 OR2C3 81472 1555018_at 0.0686 0.1904
GSE53622 OR2C3 81472 15762 0.1657 0.0112
GSE53624 OR2C3 81472 15762 0.2748 0.0001
GSE63941 OR2C3 81472 1555018_at 0.0072 0.9629
GSE77861 OR2C3 81472 1555018_at -0.1350 0.0907
GSE97050 OR2C3 81472 A_33_P3209802 0.0299 0.8886

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by OR2C3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of OR2C3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 OR2C3 81472 7 1 22
GSE20123 OR2C3 81472 7 1 22
GSE43470 OR2C3 81472 4 3 36
GSE46452 OR2C3 81472 4 2 53
GSE47630 OR2C3 81472 15 1 24
GSE54993 OR2C3 81472 0 6 64
GSE54994 OR2C3 81472 18 0 35
GSE60625 OR2C3 81472 0 0 11
GSE74703 OR2C3 81472 4 1 31
GSE74704 OR2C3 81472 2 0 18
TCGA OR2C3 81472 45 4 47

Total number of gains: 106; Total number of losses: 19; Total Number of normals: 363.  


 

Somatic mutations of OR2C3:

 

Generating mutation plots.

 

Highly correlated genes for OR2C3:

 

Showing top 20/370 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
OR2C3TMEM2350.851343303
OR2C3SLC6A30.805666303
OR2C3STRC0.80167303
OR2C3DCDC10.795723303
OR2C3C10orf910.787108303
OR2C3C19orf710.777358303
OR2C3ATCAY0.772155303
OR2C3NTNG20.770288303
OR2C3PRLH0.769166303
OR2C3PLA2G2C0.768345303
OR2C3OR2T10.768043303
OR2C3YY20.767194303
OR2C3ZNF5270.766508303
OR2C3CLTCL10.765393303
OR2C3KRTAP10-120.761149303
OR2C3LHB0.75883303
OR2C3CIB30.756178404
OR2C3ST8SIA30.755611303
OR2C3BTNL20.754016404
OR2C3MRGPRG0.749781303

For details and further investigation, click here