| Full name: keratin associated protein 1-5 | Alias Symbol: KAP1.5 | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 83895 | HGNC ID: HGNC:16777 | Ensembl Gene: ENSG00000221852 | OMIM ID: 608822 |
| Drug and gene relationship at DGIdb | |||
Expression of KRTAP1-5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRTAP1-5 | 83895 | 233533_at | -0.1350 | 0.5517 | |
| GSE26886 | KRTAP1-5 | 83895 | 233533_at | -0.1123 | 0.3577 | |
| GSE45670 | KRTAP1-5 | 83895 | 233533_at | 0.0358 | 0.7001 | |
| GSE53622 | KRTAP1-5 | 83895 | 22613 | 0.2672 | 0.0025 | |
| GSE53624 | KRTAP1-5 | 83895 | 22613 | 0.1576 | 0.0087 | |
| GSE63941 | KRTAP1-5 | 83895 | 233533_at | -4.6996 | 0.0007 | |
| GSE77861 | KRTAP1-5 | 83895 | 233533_at | -0.1036 | 0.4632 | |
| TCGA | KRTAP1-5 | 83895 | RNAseq | 2.0718 | 0.0609 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by KRTAP1-5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRTAP1-5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRTAP1-5 | 83895 | 7 | 2 | 21 | |
| GSE20123 | KRTAP1-5 | 83895 | 7 | 2 | 21 | |
| GSE43470 | KRTAP1-5 | 83895 | 1 | 2 | 40 | |
| GSE46452 | KRTAP1-5 | 83895 | 34 | 0 | 25 | |
| GSE47630 | KRTAP1-5 | 83895 | 8 | 1 | 31 | |
| GSE54993 | KRTAP1-5 | 83895 | 3 | 4 | 63 | |
| GSE54994 | KRTAP1-5 | 83895 | 8 | 5 | 40 | |
| GSE60625 | KRTAP1-5 | 83895 | 4 | 0 | 7 | |
| GSE74703 | KRTAP1-5 | 83895 | 1 | 1 | 34 | |
| GSE74704 | KRTAP1-5 | 83895 | 5 | 1 | 14 |
Total number of gains: 78; Total number of losses: 18; Total Number of normals: 296.
Somatic mutations of KRTAP1-5:
Generating mutation plots.
Highly correlated genes for KRTAP1-5:
Showing top 20/66 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRTAP1-5 | NR4A3 | 0.734817 | 3 | 0 | 3 |
| KRTAP1-5 | WDR63 | 0.678734 | 3 | 0 | 3 |
| KRTAP1-5 | PDCD1LG2 | 0.666658 | 3 | 0 | 3 |
| KRTAP1-5 | ZNF667 | 0.660802 | 3 | 0 | 3 |
| KRTAP1-5 | NYAP2 | 0.65851 | 3 | 0 | 3 |
| KRTAP1-5 | LUZP4 | 0.654418 | 3 | 0 | 3 |
| KRTAP1-5 | CNTNAP1 | 0.649928 | 4 | 0 | 4 |
| KRTAP1-5 | CDK15 | 0.631342 | 4 | 0 | 3 |
| KRTAP1-5 | OR10H3 | 0.630723 | 4 | 0 | 4 |
| KRTAP1-5 | PATE2 | 0.630426 | 3 | 0 | 3 |
| KRTAP1-5 | SVEP1 | 0.626635 | 3 | 0 | 3 |
| KRTAP1-5 | LCT | 0.626429 | 4 | 0 | 3 |
| KRTAP1-5 | TMEM225 | 0.626148 | 4 | 0 | 3 |
| KRTAP1-5 | WNT6 | 0.621888 | 5 | 0 | 3 |
| KRTAP1-5 | TAGLN3 | 0.620452 | 3 | 0 | 3 |
| KRTAP1-5 | EPB41L2 | 0.616323 | 3 | 0 | 3 |
| KRTAP1-5 | GVQW1 | 0.607541 | 4 | 0 | 3 |
| KRTAP1-5 | WNT2 | 0.604174 | 3 | 0 | 3 |
| KRTAP1-5 | LSAMP | 0.602609 | 3 | 0 | 3 |
| KRTAP1-5 | OR4D1 | 0.602255 | 4 | 0 | 3 |
For details and further investigation, click here
