| Full name: tripartite motif containing 72 | Alias Symbol: MG53 | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 493829 | HGNC ID: HGNC:32671 | Ensembl Gene: ENSG00000177238 | OMIM ID: 613288 |
| Drug and gene relationship at DGIdb | |||
Expression of TRIM72:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRIM72 | 493829 | 1554803_s_at | -0.1778 | 0.4798 | |
| GSE26886 | TRIM72 | 493829 | 1554803_s_at | 0.1243 | 0.5156 | |
| GSE45670 | TRIM72 | 493829 | 1554803_s_at | 0.0774 | 0.4385 | |
| GSE53622 | TRIM72 | 493829 | 23394 | 0.0604 | 0.6421 | |
| GSE53624 | TRIM72 | 493829 | 23394 | -0.3669 | 0.0014 | |
| GSE63941 | TRIM72 | 493829 | 1554803_s_at | 0.1999 | 0.6121 | |
| GSE77861 | TRIM72 | 493829 | 1554803_s_at | -0.1297 | 0.2205 | |
| SRP007169 | TRIM72 | 493829 | RNAseq | 0.3747 | 0.5101 | |
| SRP064894 | TRIM72 | 493829 | RNAseq | -0.0661 | 0.7685 | |
| SRP133303 | TRIM72 | 493829 | RNAseq | 0.1833 | 0.1776 | |
| SRP159526 | TRIM72 | 493829 | RNAseq | -0.1911 | 0.5804 | |
| SRP193095 | TRIM72 | 493829 | RNAseq | 0.0333 | 0.8254 | |
| SRP219564 | TRIM72 | 493829 | RNAseq | 0.0334 | 0.9170 | |
| TCGA | TRIM72 | 493829 | RNAseq | 3.5541 | 0.0032 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TRIM72 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRIM72:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRIM72 | 493829 | 4 | 5 | 21 | |
| GSE20123 | TRIM72 | 493829 | 4 | 4 | 22 | |
| GSE43470 | TRIM72 | 493829 | 3 | 3 | 37 | |
| GSE46452 | TRIM72 | 493829 | 38 | 1 | 20 | |
| GSE47630 | TRIM72 | 493829 | 11 | 7 | 22 | |
| GSE54993 | TRIM72 | 493829 | 2 | 5 | 63 | |
| GSE54994 | TRIM72 | 493829 | 5 | 9 | 39 | |
| GSE60625 | TRIM72 | 493829 | 4 | 0 | 7 | |
| GSE74703 | TRIM72 | 493829 | 3 | 2 | 31 | |
| GSE74704 | TRIM72 | 493829 | 2 | 2 | 16 | |
| TCGA | TRIM72 | 493829 | 20 | 10 | 66 |
Total number of gains: 96; Total number of losses: 48; Total Number of normals: 344.
Somatic mutations of TRIM72:
Generating mutation plots.
Highly correlated genes for TRIM72:
Showing all 10 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRIM72 | SLC25A18 | 0.688329 | 3 | 0 | 3 |
| TRIM72 | KRT12 | 0.605509 | 4 | 0 | 3 |
| TRIM72 | HUS1B | 0.583918 | 3 | 0 | 3 |
| TRIM72 | CEND1 | 0.581739 | 3 | 0 | 3 |
| TRIM72 | PNMT | 0.58081 | 4 | 0 | 3 |
| TRIM72 | ZDHHC1 | 0.573736 | 3 | 0 | 3 |
| TRIM72 | RPH3AL | 0.553557 | 4 | 0 | 3 |
| TRIM72 | TSGA10IP | 0.521854 | 5 | 0 | 4 |
| TRIM72 | C11orf16 | 0.516959 | 6 | 0 | 3 |
| TRIM72 | SIT1 | 0.516061 | 5 | 0 | 3 |
For details and further investigation, click here
