| Full name: HUS1 checkpoint clamp component B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6p25.3 | ||
| Entrez ID: 135458 | HGNC ID: HGNC:16485 | Ensembl Gene: ENSG00000188996 | OMIM ID: 609713 |
| Drug and gene relationship at DGIdb | |||
Expression of HUS1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HUS1B | 135458 | 1553660_at | -0.1693 | 0.4811 | |
| GSE26886 | HUS1B | 135458 | 1553660_at | 0.0249 | 0.8709 | |
| GSE45670 | HUS1B | 135458 | 1553660_at | -0.0527 | 0.6392 | |
| GSE63941 | HUS1B | 135458 | 1553660_at | 0.1687 | 0.2457 | |
| GSE77861 | HUS1B | 135458 | 1553660_at | -0.2729 | 0.0647 | |
| GSE97050 | HUS1B | 135458 | A_23_P133739 | 0.1690 | 0.5008 | |
| TCGA | HUS1B | 135458 | RNAseq | 2.1225 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by HUS1B expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of HUS1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HUS1B | 135458 | 3 | 5 | 22 | |
| GSE20123 | HUS1B | 135458 | 3 | 5 | 22 | |
| GSE43470 | HUS1B | 135458 | 9 | 2 | 32 | |
| GSE46452 | HUS1B | 135458 | 1 | 10 | 48 | |
| GSE47630 | HUS1B | 135458 | 7 | 8 | 25 | |
| GSE54993 | HUS1B | 135458 | 1 | 3 | 66 | |
| GSE54994 | HUS1B | 135458 | 9 | 2 | 42 | |
| GSE60625 | HUS1B | 135458 | 0 | 1 | 10 | |
| GSE74703 | HUS1B | 135458 | 8 | 2 | 26 | |
| GSE74704 | HUS1B | 135458 | 2 | 2 | 16 | |
| TCGA | HUS1B | 135458 | 16 | 29 | 51 |
Total number of gains: 59; Total number of losses: 69; Total Number of normals: 360.
Somatic mutations of HUS1B:
Generating mutation plots.
Highly correlated genes for HUS1B:
Showing top 20/160 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HUS1B | DPEP3 | 0.710571 | 4 | 0 | 4 |
| HUS1B | WDR38 | 0.706425 | 4 | 0 | 4 |
| HUS1B | CCL13 | 0.687094 | 3 | 0 | 3 |
| HUS1B | ANKRD33 | 0.686904 | 4 | 0 | 4 |
| HUS1B | BCL2L15 | 0.681017 | 3 | 0 | 3 |
| HUS1B | ZFR2 | 0.67819 | 3 | 0 | 3 |
| HUS1B | CBLN4 | 0.677726 | 3 | 0 | 3 |
| HUS1B | PRDM12 | 0.677369 | 4 | 0 | 4 |
| HUS1B | APOA4 | 0.676946 | 3 | 0 | 3 |
| HUS1B | C4BPB | 0.673383 | 4 | 0 | 3 |
| HUS1B | DOCK2 | 0.668517 | 3 | 0 | 3 |
| HUS1B | LRRC19 | 0.666028 | 3 | 0 | 3 |
| HUS1B | FOLR2 | 0.660843 | 3 | 0 | 3 |
| HUS1B | MMD2 | 0.658065 | 3 | 0 | 3 |
| HUS1B | OR1J4 | 0.65693 | 3 | 0 | 3 |
| HUS1B | LINC00290 | 0.65514 | 3 | 0 | 3 |
| HUS1B | GPR26 | 0.642861 | 3 | 0 | 3 |
| HUS1B | GALK1 | 0.641162 | 3 | 0 | 3 |
| HUS1B | PKLR | 0.640266 | 4 | 0 | 3 |
| HUS1B | LINC01342 | 0.637848 | 3 | 0 | 3 |
For details and further investigation, click here
