CEND1

 

Full name: cell cycle exit and neuronal differentiation 1 Alias Symbol: FLJ90066|BM88
Type: protein-coding gene Cytoband: 11p15.5
Entrez ID: 51286 HGNC ID: HGNC:24153 Ensembl Gene: ENSG00000184524 OMIM ID: 608213
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of CEND1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CEND1 51286 219591_at -0.0934 0.6712
GSE20347 CEND1 51286 219591_at 0.0172 0.8805
GSE23400 CEND1 51286 219591_at -0.1249 0.0013
GSE26886 CEND1 51286 219591_at -0.0187 0.9001
GSE29001 CEND1 51286 219591_at -0.1229 0.5169
GSE38129 CEND1 51286 219591_at -0.1548 0.1230
GSE45670 CEND1 51286 219591_at 0.0766 0.4701
GSE53622 CEND1 51286 41802 -0.1361 0.1006
GSE53624 CEND1 51286 41802 0.1415 0.1516
GSE63941 CEND1 51286 219591_at -0.1446 0.3031
GSE77861 CEND1 51286 219591_at -0.0525 0.7017
GSE97050 CEND1 51286 A_33_P3323945 -0.3034 0.3631
SRP133303 CEND1 51286 RNAseq -0.2280 0.4312
SRP219564 CEND1 51286 RNAseq -1.2627 0.2371
TCGA CEND1 51286 RNAseq -0.2828 0.4984

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by CEND1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of CEND1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CEND1 51286 1 11 18
GSE20123 CEND1 51286 1 12 17
GSE43470 CEND1 51286 1 10 32
GSE46452 CEND1 51286 7 8 44
GSE47630 CEND1 51286 4 12 24
GSE54993 CEND1 51286 3 1 66
GSE54994 CEND1 51286 1 12 40
GSE60625 CEND1 51286 0 0 11
GSE74703 CEND1 51286 1 8 27
GSE74704 CEND1 51286 0 8 12
TCGA CEND1 51286 8 38 50

Total number of gains: 27; Total number of losses: 120; Total Number of normals: 341.  


 

Somatic mutations of CEND1:

 

Generating mutation plots.

 

Highly correlated genes for CEND1:

 

Showing top 20/1096 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CEND1OSBPL50.79029303
CEND1TCP100.749903404
CEND1C22orf230.747191303
CEND1TSKS0.739145303
CEND1BCL2L100.730628404
CEND1RGL40.71433303
CEND1PGC0.712725505
CEND1CD2470.711972303
CEND1RNF1230.706002403
CEND1MAPK8IP20.7047606
CEND1AMACR0.701062404
CEND1REG3A0.697968403
CEND1CDK200.693455303
CEND1CYP3A40.682447504
CEND1IGFALS0.682285605
CEND1PTGDR20.68216403
CEND1SEC14L30.68123303
CEND1NOG0.681065303
CEND1CYP2D60.680602807
CEND1S100A50.679859606

For details and further investigation, click here