| Full name: rabphilin 3A like (without C2 domains) | Alias Symbol: Noc2 | ||
| Type: protein-coding gene | Cytoband: 17p13.3 | ||
| Entrez ID: 9501 | HGNC ID: HGNC:10296 | Ensembl Gene: ENSG00000181031 | OMIM ID: 604881 |
| Drug and gene relationship at DGIdb | |||
Expression of RPH3AL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPH3AL | 9501 | 221614_s_at | 0.0009 | 0.9995 | |
| GSE20347 | RPH3AL | 9501 | 221614_s_at | -0.1564 | 0.5399 | |
| GSE23400 | RPH3AL | 9501 | 221614_s_at | -0.2259 | 0.0005 | |
| GSE26886 | RPH3AL | 9501 | 238120_at | 0.0397 | 0.7710 | |
| GSE29001 | RPH3AL | 9501 | 221614_s_at | -0.2866 | 0.4054 | |
| GSE38129 | RPH3AL | 9501 | 221614_s_at | -0.2666 | 0.1955 | |
| GSE45670 | RPH3AL | 9501 | 238120_at | 0.1166 | 0.2670 | |
| GSE53622 | RPH3AL | 9501 | 42191 | -0.5289 | 0.0046 | |
| GSE53624 | RPH3AL | 9501 | 42191 | -0.5375 | 0.0001 | |
| GSE63941 | RPH3AL | 9501 | 238120_at | 0.0154 | 0.9438 | |
| GSE77861 | RPH3AL | 9501 | 221614_s_at | -0.1015 | 0.4957 | |
| GSE97050 | RPH3AL | 9501 | A_23_P94819 | 0.2947 | 0.2289 | |
| SRP007169 | RPH3AL | 9501 | RNAseq | -0.3611 | 0.7360 | |
| SRP064894 | RPH3AL | 9501 | RNAseq | 0.3774 | 0.2178 | |
| SRP133303 | RPH3AL | 9501 | RNAseq | -0.8800 | 0.0152 | |
| SRP159526 | RPH3AL | 9501 | RNAseq | -2.2891 | 0.0000 | |
| SRP193095 | RPH3AL | 9501 | RNAseq | -0.4214 | 0.1376 | |
| SRP219564 | RPH3AL | 9501 | RNAseq | 0.1367 | 0.8251 | |
| TCGA | RPH3AL | 9501 | RNAseq | -0.8967 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RPH3AL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPH3AL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPH3AL | 9501 | 5 | 4 | 21 | |
| GSE20123 | RPH3AL | 9501 | 5 | 5 | 20 | |
| GSE43470 | RPH3AL | 9501 | 1 | 7 | 35 | |
| GSE46452 | RPH3AL | 9501 | 34 | 1 | 24 | |
| GSE47630 | RPH3AL | 9501 | 8 | 1 | 31 | |
| GSE54993 | RPH3AL | 9501 | 8 | 3 | 59 | |
| GSE54994 | RPH3AL | 9501 | 7 | 9 | 37 | |
| GSE60625 | RPH3AL | 9501 | 4 | 0 | 7 | |
| GSE74703 | RPH3AL | 9501 | 1 | 4 | 31 | |
| GSE74704 | RPH3AL | 9501 | 3 | 2 | 15 | |
| TCGA | RPH3AL | 9501 | 19 | 21 | 56 |
Total number of gains: 95; Total number of losses: 57; Total Number of normals: 336.
Somatic mutations of RPH3AL:
Generating mutation plots.
Highly correlated genes for RPH3AL:
Showing top 20/127 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPH3AL | LY9 | 0.735702 | 4 | 0 | 4 |
| RPH3AL | RNF31 | 0.732338 | 3 | 0 | 3 |
| RPH3AL | ABCB7 | 0.73125 | 3 | 0 | 3 |
| RPH3AL | VPS28 | 0.70565 | 3 | 0 | 3 |
| RPH3AL | INO80B | 0.704289 | 3 | 0 | 3 |
| RPH3AL | MAPK11 | 0.681917 | 3 | 0 | 3 |
| RPH3AL | CLDND2 | 0.67624 | 3 | 0 | 3 |
| RPH3AL | SIRPG | 0.673482 | 3 | 0 | 3 |
| RPH3AL | ROPN1 | 0.671476 | 3 | 0 | 3 |
| RPH3AL | MAST2 | 0.670992 | 3 | 0 | 3 |
| RPH3AL | HIC2 | 0.670581 | 3 | 0 | 3 |
| RPH3AL | AGBL4 | 0.666893 | 3 | 0 | 3 |
| RPH3AL | ZNF155 | 0.665454 | 3 | 0 | 3 |
| RPH3AL | HIVEP3 | 0.663509 | 3 | 0 | 3 |
| RPH3AL | DNAH7 | 0.662999 | 3 | 0 | 3 |
| RPH3AL | HS3ST3B1 | 0.662606 | 3 | 0 | 3 |
| RPH3AL | FRMD8 | 0.661323 | 3 | 0 | 3 |
| RPH3AL | TIGD6 | 0.652347 | 3 | 0 | 3 |
| RPH3AL | CD74 | 0.649416 | 3 | 0 | 3 |
| RPH3AL | HLA-E | 0.647935 | 4 | 0 | 3 |
For details and further investigation, click here
