| Full name: zinc finger DHHC-type containing 1 | Alias Symbol: HSU90653|ZNF377 | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 29800 | HGNC ID: HGNC:17916 | Ensembl Gene: ENSG00000159714 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZDHHC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZDHHC1 | 29800 | 228637_at | -0.2176 | 0.7376 | |
| GSE26886 | ZDHHC1 | 29800 | 237228_at | 0.1803 | 0.1301 | |
| GSE45670 | ZDHHC1 | 29800 | 228637_at | 0.1212 | 0.4072 | |
| GSE63941 | ZDHHC1 | 29800 | 228637_at | -0.3343 | 0.1683 | |
| GSE77861 | ZDHHC1 | 29800 | 237228_at | -0.2137 | 0.0989 | |
| GSE97050 | ZDHHC1 | 29800 | A_23_P66038 | 0.1234 | 0.7345 | |
| SRP007169 | ZDHHC1 | 29800 | RNAseq | 0.6881 | 0.3670 | |
| SRP064894 | ZDHHC1 | 29800 | RNAseq | 0.6450 | 0.0226 | |
| SRP133303 | ZDHHC1 | 29800 | RNAseq | 0.3705 | 0.0653 | |
| SRP159526 | ZDHHC1 | 29800 | RNAseq | 1.1210 | 0.0000 | |
| SRP193095 | ZDHHC1 | 29800 | RNAseq | 1.0404 | 0.0000 | |
| SRP219564 | ZDHHC1 | 29800 | RNAseq | -0.0153 | 0.9777 | |
| TCGA | ZDHHC1 | 29800 | RNAseq | 0.0996 | 0.3645 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ZDHHC1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ZDHHC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZDHHC1 | 29800 | 9 | 2 | 19 | |
| GSE20123 | ZDHHC1 | 29800 | 9 | 2 | 19 | |
| GSE43470 | ZDHHC1 | 29800 | 1 | 9 | 33 | |
| GSE46452 | ZDHHC1 | 29800 | 38 | 1 | 20 | |
| GSE47630 | ZDHHC1 | 29800 | 10 | 8 | 22 | |
| GSE54993 | ZDHHC1 | 29800 | 2 | 4 | 64 | |
| GSE54994 | ZDHHC1 | 29800 | 8 | 10 | 35 | |
| GSE60625 | ZDHHC1 | 29800 | 4 | 0 | 7 | |
| GSE74703 | ZDHHC1 | 29800 | 1 | 6 | 29 | |
| GSE74704 | ZDHHC1 | 29800 | 5 | 1 | 14 | |
| TCGA | ZDHHC1 | 29800 | 29 | 12 | 55 |
Total number of gains: 116; Total number of losses: 55; Total Number of normals: 317.
Somatic mutations of ZDHHC1:
Generating mutation plots.
Highly correlated genes for ZDHHC1:
Showing top 20/151 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZDHHC1 | FGF16 | 0.795773 | 3 | 0 | 3 |
| ZDHHC1 | NLGN4X | 0.781467 | 3 | 0 | 3 |
| ZDHHC1 | PTP4A3 | 0.771478 | 3 | 0 | 3 |
| ZDHHC1 | GATA6 | 0.735351 | 3 | 0 | 3 |
| ZDHHC1 | CCR10 | 0.734828 | 3 | 0 | 3 |
| ZDHHC1 | USP2 | 0.723327 | 3 | 0 | 3 |
| ZDHHC1 | ZNF214 | 0.714586 | 3 | 0 | 3 |
| ZDHHC1 | PRDM8 | 0.705654 | 3 | 0 | 3 |
| ZDHHC1 | CRLF1 | 0.704735 | 3 | 0 | 3 |
| ZDHHC1 | SSC5D | 0.701672 | 3 | 0 | 3 |
| ZDHHC1 | MAST2 | 0.700912 | 3 | 0 | 3 |
| ZDHHC1 | PLIN4 | 0.6982 | 3 | 0 | 3 |
| ZDHHC1 | CHADL | 0.693515 | 3 | 0 | 3 |
| ZDHHC1 | C2CD4B | 0.693409 | 3 | 0 | 3 |
| ZDHHC1 | ZNF653 | 0.691893 | 4 | 0 | 4 |
| ZDHHC1 | HNF1A | 0.691351 | 3 | 0 | 3 |
| ZDHHC1 | APC2 | 0.690447 | 3 | 0 | 3 |
| ZDHHC1 | LINC00028 | 0.687766 | 3 | 0 | 3 |
| ZDHHC1 | C3orf22 | 0.680316 | 3 | 0 | 3 |
| ZDHHC1 | C20orf202 | 0.678479 | 3 | 0 | 3 |
For details and further investigation, click here
