UPP2

 

Full name: uridine phosphorylase 2 Alias Symbol: UPASE2|UP2|UDRPASE2
Type: protein-coding gene Cytoband: 2q24.1
Entrez ID: 151531 HGNC ID: HGNC:23061 Ensembl Gene: ENSG00000007001 OMIM ID: 617340
Drug and gene relationship at DGIdb

 

Expression of UPP2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 UPP2 151531 233155_at 0.0609 0.7804
GSE26886 UPP2 151531 233155_at -0.0218 0.8360
GSE45670 UPP2 151531 233155_at 0.0648 0.4884
GSE53622 UPP2 151531 37407 -0.0461 0.7261
GSE53624 UPP2 151531 37407 -0.0655 0.4513
GSE63941 UPP2 151531 233155_at 0.0962 0.5396
GSE77861 UPP2 151531 233155_at -0.1304 0.2523
SRP133303 UPP2 151531 RNAseq -0.5668 0.0885
TCGA UPP2 151531 RNAseq 0.9404 0.4607

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by UPP2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of UPP2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 UPP2 151531 4 1 25
GSE20123 UPP2 151531 4 1 25
GSE43470 UPP2 151531 4 1 38
GSE46452 UPP2 151531 1 4 54
GSE47630 UPP2 151531 5 3 32
GSE54993 UPP2 151531 0 4 66
GSE54994 UPP2 151531 11 2 40
GSE60625 UPP2 151531 0 3 8
GSE74703 UPP2 151531 3 1 32
GSE74704 UPP2 151531 3 0 17
TCGA UPP2 151531 22 10 64

Total number of gains: 57; Total number of losses: 30; Total Number of normals: 401.  

 

Somatic mutations of UPP2:

 

Generating mutation plots.

 

Highly correlated genes for UPP2:

 

Showing all 11 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
UPP2OBP2B0.734967303
UPP2CYP1B1-AS10.627501303
UPP2HABP20.624565303
UPP2WFDC60.5872303
UPP2RTEL10.56008403
UPP2L1CAM0.543788303
UPP2UNC13A0.542528303
UPP2GDF20.531288303
UPP2NYX0.524782503
UPP2APC20.519096403
UPP2DEFA40.50813403

For details and further investigation, click here