| Full name: WAP four-disulfide core domain 6 | Alias Symbol: dJ461P17.11|WAP6 | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 140870 | HGNC ID: HGNC:16164 | Ensembl Gene: ENSG00000243543 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of WFDC6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WFDC6 | 140870 | 1552396_at | 0.2068 | 0.3600 | |
| GSE26886 | WFDC6 | 140870 | 1552396_at | 0.0749 | 0.4214 | |
| GSE45670 | WFDC6 | 140870 | 1552396_at | 0.0805 | 0.2821 | |
| GSE53622 | WFDC6 | 140870 | 22173 | 0.4438 | 0.0246 | |
| GSE53624 | WFDC6 | 140870 | 22173 | 0.4663 | 0.0077 | |
| GSE63941 | WFDC6 | 140870 | 1552396_at | -0.0185 | 0.9230 | |
| GSE77861 | WFDC6 | 140870 | 1552396_at | 0.0122 | 0.9071 | |
| GSE97050 | WFDC6 | 140870 | A_33_P3285815 | -0.0441 | 0.8315 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by WFDC6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WFDC6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WFDC6 | 140870 | 14 | 1 | 15 | |
| GSE20123 | WFDC6 | 140870 | 14 | 1 | 15 | |
| GSE43470 | WFDC6 | 140870 | 12 | 1 | 30 | |
| GSE46452 | WFDC6 | 140870 | 29 | 0 | 30 | |
| GSE47630 | WFDC6 | 140870 | 24 | 1 | 15 | |
| GSE54993 | WFDC6 | 140870 | 0 | 17 | 53 | |
| GSE54994 | WFDC6 | 140870 | 25 | 0 | 28 | |
| GSE60625 | WFDC6 | 140870 | 0 | 0 | 11 | |
| GSE74703 | WFDC6 | 140870 | 10 | 1 | 25 | |
| GSE74704 | WFDC6 | 140870 | 10 | 0 | 10 | |
| TCGA | WFDC6 | 140870 | 45 | 3 | 48 |
Total number of gains: 183; Total number of losses: 25; Total Number of normals: 280.
Somatic mutations of WFDC6:
Generating mutation plots.
Highly correlated genes for WFDC6:
Showing top 20/99 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WFDC6 | MEGF10 | 0.755512 | 3 | 0 | 3 |
| WFDC6 | ARHGEF1 | 0.705185 | 3 | 0 | 3 |
| WFDC6 | TRIM10 | 0.66151 | 3 | 0 | 3 |
| WFDC6 | PRAMEF5 | 0.660784 | 3 | 0 | 3 |
| WFDC6 | POLR3G | 0.652216 | 3 | 0 | 3 |
| WFDC6 | VHL | 0.651941 | 4 | 0 | 3 |
| WFDC6 | SLC26A1 | 0.644212 | 4 | 0 | 4 |
| WFDC6 | CTBP1-AS | 0.638703 | 3 | 0 | 3 |
| WFDC6 | OR10H1 | 0.635098 | 4 | 0 | 3 |
| WFDC6 | MRPS16 | 0.634748 | 3 | 0 | 3 |
| WFDC6 | NAT8B | 0.632121 | 3 | 0 | 3 |
| WFDC6 | SBNO2 | 0.629199 | 3 | 0 | 3 |
| WFDC6 | TRIM55 | 0.62359 | 4 | 0 | 3 |
| WFDC6 | F2RL3 | 0.623339 | 4 | 0 | 3 |
| WFDC6 | LINC01007 | 0.621182 | 3 | 0 | 3 |
| WFDC6 | DEFB123 | 0.62078 | 5 | 0 | 3 |
| WFDC6 | STRC | 0.620724 | 3 | 0 | 3 |
| WFDC6 | LINC00566 | 0.616639 | 3 | 0 | 3 |
| WFDC6 | KRTAP4-8 | 0.61396 | 3 | 0 | 3 |
| WFDC6 | PROCA1 | 0.613419 | 4 | 0 | 3 |
For details and further investigation, click here
