| Full name: unc-13 homolog A | Alias Symbol: KIAA1032|Munc13-1 | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 23025 | HGNC ID: HGNC:23150 | Ensembl Gene: ENSG00000130477 | OMIM ID: 609894 |
Expression of UNC13A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UNC13A | 23025 | 214817_at | 0.2561 | 0.3234 | |
| GSE20347 | UNC13A | 23025 | 214817_at | 0.0342 | 0.6406 | |
| GSE23400 | UNC13A | 23025 | 214817_at | -0.0797 | 0.0038 | |
| GSE26886 | UNC13A | 23025 | 214817_at | 0.0375 | 0.7660 | |
| GSE29001 | UNC13A | 23025 | 214817_at | 0.0151 | 0.9215 | |
| GSE38129 | UNC13A | 23025 | 214817_at | -0.0739 | 0.4987 | |
| GSE45670 | UNC13A | 23025 | 227453_at | -0.0531 | 0.6434 | |
| GSE53622 | UNC13A | 23025 | 42502 | 0.0208 | 0.9279 | |
| GSE53624 | UNC13A | 23025 | 42502 | 0.2503 | 0.0241 | |
| GSE63941 | UNC13A | 23025 | 227453_at | 0.1675 | 0.4751 | |
| GSE77861 | UNC13A | 23025 | 227453_at | -0.0397 | 0.7511 | |
| SRP133303 | UNC13A | 23025 | RNAseq | -0.0637 | 0.7946 | |
| SRP159526 | UNC13A | 23025 | RNAseq | 1.2468 | 0.0204 | |
| SRP193095 | UNC13A | 23025 | RNAseq | 0.5661 | 0.0149 | |
| SRP219564 | UNC13A | 23025 | RNAseq | 0.5538 | 0.2651 | |
| TCGA | UNC13A | 23025 | RNAseq | -0.9025 | 0.0206 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by UNC13A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UNC13A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UNC13A | 23025 | 4 | 4 | 22 | |
| GSE20123 | UNC13A | 23025 | 3 | 2 | 25 | |
| GSE43470 | UNC13A | 23025 | 2 | 6 | 35 | |
| GSE46452 | UNC13A | 23025 | 47 | 1 | 11 | |
| GSE47630 | UNC13A | 23025 | 4 | 8 | 28 | |
| GSE54993 | UNC13A | 23025 | 15 | 4 | 51 | |
| GSE54994 | UNC13A | 23025 | 6 | 14 | 33 | |
| GSE60625 | UNC13A | 23025 | 9 | 0 | 2 | |
| GSE74703 | UNC13A | 23025 | 2 | 4 | 30 | |
| GSE74704 | UNC13A | 23025 | 0 | 2 | 18 | |
| TCGA | UNC13A | 23025 | 17 | 9 | 70 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of UNC13A:
Generating mutation plots.
Highly correlated genes for UNC13A:
Showing top 20/132 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UNC13A | GGTLC1 | 0.646849 | 5 | 0 | 5 |
| UNC13A | CACTIN | 0.642048 | 3 | 0 | 3 |
| UNC13A | DGKZ | 0.629225 | 3 | 0 | 3 |
| UNC13A | GATA6-AS1 | 0.622591 | 3 | 0 | 3 |
| UNC13A | IGF2-AS | 0.620106 | 4 | 0 | 3 |
| UNC13A | MASP2 | 0.614606 | 3 | 0 | 3 |
| UNC13A | ASTN1 | 0.613353 | 3 | 0 | 3 |
| UNC13A | APOBEC1 | 0.613054 | 3 | 0 | 3 |
| UNC13A | SIGLEC8 | 0.612377 | 3 | 0 | 3 |
| UNC13A | NXPH4 | 0.607829 | 4 | 0 | 3 |
| UNC13A | BMP8A | 0.605572 | 3 | 0 | 3 |
| UNC13A | CNGB3 | 0.600098 | 4 | 0 | 3 |
| UNC13A | STX1A | 0.598536 | 3 | 0 | 3 |
| UNC13A | LHFPL5 | 0.598434 | 3 | 0 | 3 |
| UNC13A | CGA | 0.597718 | 5 | 0 | 4 |
| UNC13A | PTP4A3 | 0.595886 | 3 | 0 | 3 |
| UNC13A | CCDC71 | 0.594312 | 5 | 0 | 4 |
| UNC13A | TFAP4 | 0.592122 | 4 | 0 | 3 |
| UNC13A | KCNJ5 | 0.591729 | 5 | 0 | 4 |
| UNC13A | F2RL2 | 0.589694 | 4 | 0 | 3 |
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