| Full name: L1 cell adhesion molecule | Alias Symbol: CD171 | ||
| Type: protein-coding gene | Cytoband: Xq28 | ||
| Entrez ID: 3897 | HGNC ID: HGNC:6470 | Ensembl Gene: ENSG00000198910 | OMIM ID: 308840 |
| Drug and gene relationship at DGIdb | |||
L1CAM involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04360 | Axon guidance |
Expression of L1CAM:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | L1CAM | 3897 | 204584_at | -0.7726 | 0.4196 | |
| GSE20347 | L1CAM | 3897 | 204585_s_at | -0.0061 | 0.9487 | |
| GSE23400 | L1CAM | 3897 | 204584_at | -0.0347 | 0.7120 | |
| GSE26886 | L1CAM | 3897 | 204585_s_at | 0.0248 | 0.8343 | |
| GSE29001 | L1CAM | 3897 | 204585_s_at | -0.1782 | 0.2545 | |
| GSE38129 | L1CAM | 3897 | 204585_s_at | -0.1444 | 0.0706 | |
| GSE45670 | L1CAM | 3897 | 204585_s_at | 0.0454 | 0.7072 | |
| GSE53622 | L1CAM | 3897 | 119967 | -0.9223 | 0.0000 | |
| GSE53624 | L1CAM | 3897 | 41563 | 0.2713 | 0.0058 | |
| GSE63941 | L1CAM | 3897 | 204585_s_at | 0.4644 | 0.1117 | |
| GSE77861 | L1CAM | 3897 | 204585_s_at | -0.0463 | 0.6961 | |
| GSE97050 | L1CAM | 3897 | A_24_P207995 | -0.7872 | 0.1539 | |
| SRP064894 | L1CAM | 3897 | RNAseq | 0.1600 | 0.6610 | |
| SRP133303 | L1CAM | 3897 | RNAseq | 1.3801 | 0.0923 | |
| SRP159526 | L1CAM | 3897 | RNAseq | -1.0538 | 0.0346 | |
| SRP219564 | L1CAM | 3897 | RNAseq | -0.1297 | 0.8957 | |
| TCGA | L1CAM | 3897 | RNAseq | -0.4871 | 0.0451 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by L1CAM expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of L1CAM:
No record found for this gene.
Somatic mutations of L1CAM:
Generating mutation plots.
Highly correlated genes for L1CAM:
Showing top 20/693 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| L1CAM | STXBP6 | 0.850994 | 3 | 0 | 3 |
| L1CAM | PRR26 | 0.745519 | 3 | 0 | 3 |
| L1CAM | ADAMTSL1 | 0.722512 | 4 | 0 | 3 |
| L1CAM | RNF208 | 0.722396 | 3 | 0 | 3 |
| L1CAM | XKR4 | 0.712026 | 3 | 0 | 3 |
| L1CAM | CITED2 | 0.711579 | 3 | 0 | 3 |
| L1CAM | MTURN | 0.711211 | 3 | 0 | 3 |
| L1CAM | ARHGEF25 | 0.70534 | 4 | 0 | 4 |
| L1CAM | OR6B1 | 0.702492 | 3 | 0 | 3 |
| L1CAM | RYR2 | 0.698499 | 4 | 0 | 3 |
| L1CAM | LGI4 | 0.692107 | 5 | 0 | 5 |
| L1CAM | TMEM88 | 0.690126 | 4 | 0 | 3 |
| L1CAM | PAXBP1-AS1 | 0.688647 | 3 | 0 | 3 |
| L1CAM | HRC | 0.680993 | 5 | 0 | 4 |
| L1CAM | SORCS1 | 0.677075 | 4 | 0 | 4 |
| L1CAM | PGC | 0.671342 | 3 | 0 | 3 |
| L1CAM | TCTA | 0.670939 | 4 | 0 | 3 |
| L1CAM | PTCHD1 | 0.668132 | 3 | 0 | 3 |
| L1CAM | EPHA7 | 0.666261 | 4 | 0 | 3 |
| L1CAM | SLC17A2 | 0.657912 | 4 | 0 | 4 |
For details and further investigation, click here
