| Full name: growth differentiation factor 2 | Alias Symbol: BMP-9|BMP9 | ||
| Type: protein-coding gene | Cytoband: 10q11.22 | ||
| Entrez ID: 2658 | HGNC ID: HGNC:4217 | Ensembl Gene: ENSG00000263761 | OMIM ID: 605120 |
| Drug and gene relationship at DGIdb | |||
Expression of GDF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GDF2 | 2658 | 221136_at | -0.0719 | 0.7387 | |
| GSE20347 | GDF2 | 2658 | 221136_at | -0.0343 | 0.6775 | |
| GSE23400 | GDF2 | 2658 | 221136_at | -0.1590 | 0.0002 | |
| GSE26886 | GDF2 | 2658 | 221136_at | 0.2141 | 0.1345 | |
| GSE29001 | GDF2 | 2658 | 221136_at | -0.2617 | 0.0374 | |
| GSE38129 | GDF2 | 2658 | 221136_at | -0.1972 | 0.0864 | |
| GSE45670 | GDF2 | 2658 | 221136_at | -0.0467 | 0.6468 | |
| GSE53622 | GDF2 | 2658 | 15631 | -0.1667 | 0.1131 | |
| GSE53624 | GDF2 | 2658 | 15631 | -0.0295 | 0.7585 | |
| GSE63941 | GDF2 | 2658 | 221136_at | 0.1601 | 0.3474 | |
| GSE77861 | GDF2 | 2658 | 221136_at | -0.0005 | 0.9980 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GDF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GDF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GDF2 | 2658 | 2 | 5 | 23 | |
| GSE20123 | GDF2 | 2658 | 2 | 5 | 23 | |
| GSE43470 | GDF2 | 2658 | 1 | 6 | 36 | |
| GSE46452 | GDF2 | 2658 | 0 | 13 | 46 | |
| GSE47630 | GDF2 | 2658 | 4 | 13 | 23 | |
| GSE54993 | GDF2 | 2658 | 9 | 0 | 61 | |
| GSE54994 | GDF2 | 2658 | 2 | 10 | 41 | |
| GSE60625 | GDF2 | 2658 | 0 | 0 | 11 | |
| GSE74703 | GDF2 | 2658 | 1 | 3 | 32 | |
| GSE74704 | GDF2 | 2658 | 1 | 4 | 15 | |
| TCGA | GDF2 | 2658 | 16 | 18 | 62 |
Total number of gains: 38; Total number of losses: 77; Total Number of normals: 373.
Somatic mutations of GDF2:
Generating mutation plots.
Highly correlated genes for GDF2:
Showing top 20/1085 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GDF2 | CACNA1H | 0.750067 | 3 | 0 | 3 |
| GDF2 | PHLDB1 | 0.736274 | 5 | 0 | 5 |
| GDF2 | PAPOLB | 0.732476 | 3 | 0 | 3 |
| GDF2 | KCNQ1DN | 0.728371 | 8 | 0 | 8 |
| GDF2 | MORN1 | 0.718329 | 9 | 0 | 9 |
| GDF2 | CER1 | 0.717052 | 4 | 0 | 4 |
| GDF2 | MC5R | 0.71682 | 3 | 0 | 3 |
| GDF2 | NCR2 | 0.711717 | 4 | 0 | 4 |
| GDF2 | ASIC4 | 0.707126 | 8 | 0 | 6 |
| GDF2 | OPHN1 | 0.704931 | 3 | 0 | 3 |
| GDF2 | GRPR | 0.702236 | 4 | 0 | 4 |
| GDF2 | PAX7 | 0.699453 | 3 | 0 | 3 |
| GDF2 | POMC | 0.696548 | 3 | 0 | 3 |
| GDF2 | PRKACG | 0.693005 | 4 | 0 | 4 |
| GDF2 | OR12D2 | 0.690369 | 6 | 0 | 5 |
| GDF2 | DUX1 | 0.68966 | 7 | 0 | 7 |
| GDF2 | SELPLG | 0.687626 | 3 | 0 | 3 |
| GDF2 | AMN | 0.685821 | 7 | 0 | 6 |
| GDF2 | DNAJC4 | 0.685757 | 3 | 0 | 3 |
| GDF2 | FUT7 | 0.68155 | 8 | 0 | 8 |
For details and further investigation, click here
